Departments of Animal Science and Large Animal Clinical Sciences, Michigan State University, East Lansing, MI 48824, USA.
Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.
Cell. 2018 Feb 8;172(4):647-649. doi: 10.1016/j.cell.2018.01.030.
In this issue of Cell, Liu et al. (2018) report the birth of two healthy cloned macaque monkeys using fetal fibroblasts. By artificially enhancing the arsenal of epigenetic modifiers in the oocyte, the authors overcome the earliest roadblocks that take place during somatic cell nuclear transfer (SCNT).
在本期《细胞》中，刘等人（2018 年）报道了使用胎儿成纤维细胞克隆出两只健康的猕猴。通过人为增强卵母细胞中表观遗传修饰因子的储备，作者克服了体细胞核移植（SCNT）过程中最早出现的障碍。
