Dy Alexander Edward S, Lapeña José Florencio F
1 Department of Otorhinolaryngology, Philippine General Hospital, University of the Philippines Manila, Manila, Metro Manila, Philippines.
2 Department of Otorhinolaryngology, College of Medicine-Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
Ann Otol Rhinol Laryngol. 2018 Apr;127(4):253-257. doi: 10.1177/0003489418756678. Epub 2018 Feb 9.
To investigate associations between age, external auditory canal (EAC) dimensions, and cerumen retention/impaction among persons with Down syndrome (DS).
This cross-sectional study evaluated EAC dimensions, cerumen retention/impaction, and middle ear status with pneumatoscopy after extraction in 130 persons with DS. Descriptive and inferential statistics correlated age, presence of impacted/retained cerumen, and EAC diameter.
Of 260 ears in 67 males and 63 females with average age of 9.48 years, 72.3% (188) had EAC of ≤4 mm. Those ≤1 year were 4.97 times more likely to have cerumen problems than those >1 year (95% CI, 1.45-17.02, P = .011). The odds of having cerumen problems with an EAC diameter of ≤4 mm were 3.31 times higher than with a diameter of 5 mm (95% CI, 1.46-7.50, P = .004), and odds of having cerumen impaction were as much as 6.19 times higher (95% CI, 2.38-16.08, P < .001). Male gender and low-lying external ear were also associated with increased odds of cerumen problems.
There is a high prevalence of cerumen retention/impaction in persons with DS compared to the general Philippine population and a higher prevalence rate for EAC stenosis than elsewhere. A canal diameter of 4 mm and below and age 1 year or less are associated with a significantly higher likelihood of cerumen retention/impaction.
探讨唐氏综合征（DS）患者的年龄、外耳道（EAC）尺寸与耵聍潴留/嵌塞之间的关联。
这项横断面研究评估了130例DS患者在取出耵聍后通过耳镜检查的EAC尺寸、耵聍潴留/嵌塞情况及中耳状况。描述性和推断性统计分析了年龄、耵聍嵌塞/潴留情况与EAC直径之间的相关性。
在67名男性和63名女性共260只耳朵中，平均年龄为9.48岁，72.3%（188只）的EAC≤4mm。年龄≤1岁的患者出现耵聍问题的可能性是年龄>1岁患者的4.97倍（95%CI，1.45 - 17.02，P = 0.011）。EAC直径≤4mm的患者出现耵聍问题的几率比直径为5mm的患者高3.31倍（95%CI，1.46 - 7.50，P = 0.004），耵聍嵌塞的几率则高达6.19倍（95%CI，2.38 - 16.08，P < 0.001）。男性性别和低位外耳也与耵聍问题几率增加有关。
与菲律宾普通人群相比，DS患者中耵聍潴留/嵌塞的患病率较高，EAC狭窄的患病率也高于其他地区。4mm及以下的耳道直径和1岁及以下的年龄与耵聍潴留/嵌塞的可能性显著更高有关。
