Suppr超能文献

唐氏综合征患者的外耳道尺寸、年龄与耵聍潴留或嵌塞

External Auditory Canal Dimensions, Age, and Cerumen Retention or Impaction in Persons With Down Syndrome.

作者信息

Dy Alexander Edward S, Lapeña José Florencio F

机构信息

1 Department of Otorhinolaryngology, Philippine General Hospital, University of the Philippines Manila, Manila, Metro Manila, Philippines.

2 Department of Otorhinolaryngology, College of Medicine-Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.

出版信息

Ann Otol Rhinol Laryngol. 2018 Apr;127(4):253-257. doi: 10.1177/0003489418756678. Epub 2018 Feb 9.

Abstract

OBJECTIVE

To investigate associations between age, external auditory canal (EAC) dimensions, and cerumen retention/impaction among persons with Down syndrome (DS).

METHODS

This cross-sectional study evaluated EAC dimensions, cerumen retention/impaction, and middle ear status with pneumatoscopy after extraction in 130 persons with DS. Descriptive and inferential statistics correlated age, presence of impacted/retained cerumen, and EAC diameter.

RESULTS

Of 260 ears in 67 males and 63 females with average age of 9.48 years, 72.3% (188) had EAC of ≤4 mm. Those ≤1 year were 4.97 times more likely to have cerumen problems than those >1 year (95% CI, 1.45-17.02, P = .011). The odds of having cerumen problems with an EAC diameter of ≤4 mm were 3.31 times higher than with a diameter of 5 mm (95% CI, 1.46-7.50, P = .004), and odds of having cerumen impaction were as much as 6.19 times higher (95% CI, 2.38-16.08, P < .001). Male gender and low-lying external ear were also associated with increased odds of cerumen problems.

CONCLUSION

There is a high prevalence of cerumen retention/impaction in persons with DS compared to the general Philippine population and a higher prevalence rate for EAC stenosis than elsewhere. A canal diameter of 4 mm and below and age 1 year or less are associated with a significantly higher likelihood of cerumen retention/impaction.

摘要

目的

探讨唐氏综合征(DS)患者的年龄、外耳道(EAC)尺寸与耵聍潴留/嵌塞之间的关联。

方法

这项横断面研究评估了130例DS患者在取出耵聍后通过耳镜检查的EAC尺寸、耵聍潴留/嵌塞情况及中耳状况。描述性和推断性统计分析了年龄、耵聍嵌塞/潴留情况与EAC直径之间的相关性。

结果

在67名男性和63名女性共260只耳朵中,平均年龄为9.48岁,72.3%(188只)的EAC≤4mm。年龄≤1岁的患者出现耵聍问题的可能性是年龄>1岁患者的4.97倍(95%CI,1.45 - 17.02,P = 0.011)。EAC直径≤4mm的患者出现耵聍问题的几率比直径为5mm的患者高3.31倍(95%CI,1.46 - 7.50,P = 0.004),耵聍嵌塞的几率则高达6.19倍(95%CI,2.38 - 16.08,P < 0.001)。男性性别和低位外耳也与耵聍问题几率增加有关。

结论

与菲律宾普通人群相比,DS患者中耵聍潴留/嵌塞的患病率较高,EAC狭窄的患病率也高于其他地区。4mm及以下的耳道直径和1岁及以下的年龄与耵聍潴留/嵌塞的可能性显著更高有关。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验