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非酒精性脂肪性肝炎(NASH)患者的真实生活管理。

Management of patients with non-alcoholic steatohepatitis (NASH) in real life.

机构信息

Service d'Hépato-gastroentérologie Hôpitaux Universitaires de Strasbourg, INSERM UMR-S938 Université Pierre & Marie Curie, Paris, France.

出版信息

Liver Int. 2018 Feb;38 Suppl 1:52-55. doi: 10.1111/liv.13637.

DOI:10.1111/liv.13637
PMID:29427486
Abstract

Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) is a prevalent condition that is associated with the development of cirrhosis and hepatocellular carcinoma and with no approved treatment options except for lifestyle changes. Guidelines have been drafted for the management of NAFLD patients in this setting. Because of the lack of real-life cohort data, we will focus on practice surveys on the management of patients with NAFLD/NASH, which included primary care practitioners, gastroenterologists/hepatologists and other specialists from various countries. Practice patterns have been collected from interviews with practitioners or reviews of patient's files. This review discusses the screening, diagnosis and therapeutic management of NAFLD/NASH patients in real life practice, as well as adherence to guidelines.

摘要

非酒精性脂肪性肝病(NAFLD)/非酒精性脂肪性肝炎(NASH)是一种普遍存在的疾病,与肝硬化和肝细胞癌的发展有关,除了生活方式改变外,目前尚无批准的治疗方法。为此已制定了 NAFLD 患者管理指南。由于缺乏真实队列数据,我们将重点关注来自不同国家的初级保健医生、胃肠病学家/肝病学家和其他专家对 NAFLD/NASH 患者管理的实践调查。实践模式是通过对医生的访谈或对患者病历的审查收集的。这篇综述讨论了真实临床实践中 NAFLD/NASH 患者的筛查、诊断和治疗管理,以及对指南的遵循情况。

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