Cherian Tharian S, Upadhyay Gaurav A
Section of Cardiology, The University of Chicago Medicine, Pritzker School of Medicine, 5841 South Maryland Avenue, Chicago, IL 60637, USA.
Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, The University of Chicago Medicine, Pritzker School of Medicine, 5841 South Maryland Avenue, MC 9024, Chicago, IL 60637, USA.
Card Electrophysiol Clin. 2018 Mar;10(1):31-42. doi: 10.1016/j.ccep.2017.11.004. Epub 2017 Dec 1.
Long-term right ventricular pacing is associated with electrical and mechanical dyssynchrony and ultimately development of pacing-induced cardiomyopathy (PICM) in a subset of patients. Patients with a high degree of pacing burden and reduced left ventricular (LV) function prior to pacemaker implantation are at the greatest risk for developing PICM. Cardiac resynchronization therapy (CRT) has an established role in the treatment of patients with LV systolic heart failure and intraventricular delay and has been used to successfully treat PICM. This review evaluates predictors for PICM, as well as highlights the role for CRT in prevention and treatment in high risk patients.
长期右心室起搏与电和机械不同步相关，最终在一部分患者中会发展为起搏诱导的心肌病（PICM）。在植入起搏器之前起搏负担高且左心室（LV）功能降低的患者发生PICM的风险最高。心脏再同步治疗（CRT）在治疗左心室收缩性心力衰竭和室内传导延迟的患者中已确立了作用，并已成功用于治疗PICM。本综述评估了PICM的预测因素，并强调了CRT在高危患者预防和治疗中的作用。
