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术前超声引导下肩胛上神经阻滞(SNB)与术中膈神经浸润(PNI)对肺癌患者开胸术后急性同侧肩部疼痛镇痛效果的比较研究。

Comparative study on the analgesic effect of acute ipsilateral shoulder pain after open thoracotomy between preoperative ultrasound guided suprascapular nerve block (SNB) and intraoperative phrenic nerve infiltration (PNI) in cancer lung patients.

作者信息

Elfokery Bassel M, Tawfic Sahar A, Abdelrahman Abdelrahman M, Abbas Dina N, Abdelghaffar Ikramy M

机构信息

Department of Anaesthesia, National Cancer Institute, Cairo University, Egypt.

Department of Anaesthesia, National Cancer Institute, Cairo University, Egypt.

出版信息

J Egypt Natl Canc Inst. 2018 Mar;30(1):27-31. doi: 10.1016/j.jnci.2018.01.003. Epub 2018 Feb 7.

Abstract

INTRODUCTION

Acute ipsilateral shoulder pain (ISP) is a common complaint in patients after thoracotomy. The incidence ranges from 21% to 97%. Unfortunately, clinical studies did not put enough focus on ISP post thoracic surgery.

AIM OF THE WORK

This study was designed to compare the effectiveness of suprascapular nerve block (SNB) and phrenic nerve infiltration (PNI) for controlling ISP.

PATIENTS AND METHODS

One hundred and thirty-five lung cancer patients (135) scheduled for open-lung surgery were randomly allocated into three equal groups; control group: received thoracic epidural with general anesthesia, suprascapular group: (SNB) one hour before the operation with 10 ml bupivacaine plus thoracic epidural with general anesthesia and phrenic nerve group: (PNI) was performed by the operating surgeon with 10 ml bupivacaine plus thoracic epidural with general anesthesia. The visual analogue score (VAS) of ISP, rescue of ketorolac for break through shoulder pain, peak expiratory flow rate (PEFR) and arterial blood gases were measured every 6 h postoperatively for 48 h.

RESULTS

The VAS, rescue doses of ketorolc and PEFR were significantly lower in the phrenic nerve group (P-value <0.05). There was no statistically significant difference between the three groups postoperatively as regards arterial blood gases (P-value >0.05).

CONCLUSION

PNI is more effective than SNB for ISP.

摘要

引言

急性同侧肩部疼痛(ISP)是开胸术后患者的常见主诉。发病率在21%至97%之间。遗憾的是,临床研究对胸外科手术后的ISP关注不足。

研究目的

本研究旨在比较肩胛上神经阻滞(SNB)和膈神经浸润(PNI)控制ISP的效果。

患者与方法

135例计划行开胸肺手术的肺癌患者被随机分为三组,每组人数相等;对照组:接受胸段硬膜外麻醉联合全身麻醉;肩胛上神经组:(SNB)术前1小时注射10毫升布比卡因,联合胸段硬膜外麻醉和全身麻醉;膈神经组:(PNI)由手术医生注射10毫升布比卡因,联合胸段硬膜外麻醉和全身麻醉。术后48小时内,每6小时测量一次ISP的视觉模拟评分(VAS)、用于缓解突破性肩部疼痛的酮咯酸用量、呼气峰值流速(PEFR)和动脉血气。

结果

膈神经组的VAS、酮咯酸的挽救剂量和PEFR显著更低(P值<0.05)。三组术后动脉血气方面无统计学显著差异(P值>0.05)。

结论

对于ISP,PNI比SNB更有效。

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