理解社会统治的神经机制的进展。
Advances in understanding neural mechanisms of social dominance.
机构信息
Center for Neuroscience, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Medicine, Interdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou 310058, PR China; Mental Health Center, School of Medicine, Zhejiang University, Hangzhou 310013, PR China; Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, PR China.
Brain Mind Institute, School of Life Sciences, Swiss Federal Institute of Technology Lausanne, EPFL, Lausanne, Switzerland.
出版信息
Curr Opin Neurobiol. 2018 Apr;49:99-107. doi: 10.1016/j.conb.2018.01.006. Epub 2018 Feb 8.
Dominance hierarchy profoundly impacts social animals' survival, physical and mental health and reproductive success. As the measurements of dominance hierarchy in rodents become established, it is now possible to understand the neural mechanism mediating the intrinsic and extrinsic factors determining social hierarchy. This review summarizes the latest advances in assay development for measuring dominance hierarchy in laboratory mice. It also reviews our current understandings on how activity and plasticity of specific neural circuits shape the dominance trait and mediate the 'winner effect'.
等级制度深刻影响着群居动物的生存、身心健康和繁殖成功率。随着啮齿类动物等级制度测量方法的确立，现在我们可以了解调节社会等级的内在和外在因素的神经机制。这篇综述总结了实验室中小鼠等级制度测量方法的最新进展，也回顾了我们目前对于特定神经回路的活动和可塑性如何塑造优势特征以及调节“胜利者效应”的理解。
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