Department of Pediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, Cracow, Poland.
Department of Pediatric Gastroenterology and Nutrition, Warsaw Medical University, Warsaw, Poland.
Adv Exp Med Biol. 2019;1113:83-88. doi: 10.1007/5584_2018_163.
Patients suffering from inflammatory bowel diseases (IBD) are at increased risk of infections, mainly due to immunosuppressive treatment. Moreover, infections may cause flares of IBD. Vaccination is the most effective way of preventing many infections. The aim of this study was to evaluate the vaccination status of Polish children with IBD. Individual immunization cards of children with IBD and healthy controls were reviewed. Demographic data such as age, sex, and IBD history, including therapy type, were collected. We enrolled 267 children into the study, including 214 children with IBD and 53 controls. None of the children had completed the full up-to-date routine childhood immunization schedule recommended in Poland. Controls were more than 4 times more likely to be vaccinated than the IBD patients, with the vaccines that enjoy the insurance reimbursed (OR 4.1, 95% CI 2.2-7.9). In conclusion, the study demonstrates a poor vaccination status in children suffering from IBD.
患有炎症性肠病（IBD）的患者感染风险增加，主要是由于免疫抑制治疗。此外，感染可能会导致 IBD 发作。疫苗接种是预防许多感染的最有效方法。本研究旨在评估波兰 IBD 患儿的疫苗接种状况。回顾了患有 IBD 和健康对照儿童的个人免疫接种卡。收集了年龄、性别和 IBD 病史等人口统计学数据，包括治疗类型。我们共纳入 267 名儿童进行研究，其中 214 名患有 IBD，53 名为对照。没有一个孩子完成了波兰推荐的完整的最新常规儿童免疫接种计划。对照组接种疫苗的可能性是 IBD 患者的 4 倍以上，享受保险报销的疫苗（OR 4.1，95%CI 2.2-7.9）。总之，该研究表明患有 IBD 的儿童疫苗接种状况不佳。
