Fu T, Zhang K, Zhang X W, Wang Z Y
Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Qingdao University, Qingdao 266003, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Feb 7;53(2):131-133. doi: 10.3760/cma.j.issn.1673-0860.2018.02.009.
By comparing the clinical characteristics of patulous Eustachian tube with habitual nasal extraction and those of non-Eustachian tube abnormalities, we aimed to investigate the relationship between patulous Eustachian tube and acquired cholesteatoma of middle ear. A total of 218 patients in Affiliated Hospital of Qingdao University from November 2011 to November 2016 who underwent surgical treatment and with complete data of acquired cholesteatoma of middle ear were enrolled. The patients were divided into two groups: patulous Eustachian tube with habitual nasal extraction and non-Patulous Eustachian tube. Their ages of onset , sides, characteristics of acoustic immitance, clinical manifestations, prognosis and complications were compared. The statistical analysis was carried out with SPSS 19.0 software. Among the 218 cases of acquired cholesteatoma of the middle ear, 22 cases were diagnosed as patulous Eustachian tube with habitual nasal extraction [with average age of (35.7±7.5) years]; 196 cases were diagnosed as non-patulous Eustachian tube [with average age of (47.8±20.1) years]. The average age of the patulous Eustachian tube with habitual nasal extraction was significantly lower than that of the non-patulous Eustachian tube group (=4.25, <0.01). Ratio of bilateral middle ear cholesteatoma in patulous Eustachian tube [68.2%(15/22)] was significantly higher than that of the non-patulous Eustachian tube group [18.9%(37/196)] (χ(2)=26.47, <0.01). Some acquired cholesteatoma patients are associated with the patulous Eustachian tube with habitual nasal extraction. The patients have a lower age, and are susceptible for bilateral middle ear cholesteatoma.
通过比较咽鼓管异常开放伴习惯性鼻吸气与非咽鼓管异常患者的临床特征，我们旨在研究咽鼓管异常开放与后天性中耳胆脂瘤之间的关系。选取2011年11月至2016年11月在青岛大学附属医院接受手术治疗且有完整后天性中耳胆脂瘤资料的218例患者。将患者分为两组：咽鼓管异常开放伴习惯性鼻吸气组和非咽鼓管异常开放组。比较两组患者的发病年龄、患侧、声导抗特点、临床表现、预后及并发症情况。采用SPSS 19.0软件进行统计学分析。在218例后天性中耳胆脂瘤患者中，22例被诊断为咽鼓管异常开放伴习惯性鼻吸气[平均年龄为(35.7±7.5)岁]；196例被诊断为非咽鼓管异常开放[平均年龄为(47.8±20.1)岁]。咽鼓管异常开放伴习惯性鼻吸气组的平均年龄显著低于非咽鼓管异常开放组(t=4.25，P<0.01)。咽鼓管异常开放组双侧中耳胆脂瘤的比例[68.2%(15/22)]显著高于非咽鼓管异常开放组18.9%(37/196)。部分后天性中耳胆脂瘤患者与咽鼓管异常开放伴习惯性鼻吸气有关。这些患者年龄较小，且易患双侧中耳胆脂瘤。
