Lin B, Chen Z D, Cai T Y, Wu S S, Guo Z M
Department of Orthopedics, the 175th Hospital of PLA, the Affiliated Southeast Hospital of Xiamen University, Zhangzhou 363000, China.
Zhonghua Yi Xue Za Zhi. 2018 Feb 6;98(6):422-426. doi: 10.3760/cma.j.issn.0376-2491.2018.06.005.
To investigate the clinical curative effect of C(1)-C(2) pedicle screw fixation for pediatric atlantoaxial dislocation after a long-term follow-up. From March 2005 to April 2011, a total of 12 male and 9 female patients were included, with age from 3 to 9 years old (mean, 6.1 years old). Among them, 14 cases (67%) had typeⅠinstability atlantoaxial dislocation, 7 cases (33%) had type Ⅱ reducible atlantoaxial dislocation. All 21 pediatric patients with atlantoaxial dislocation underwent posterior pedicle screw fixations. Frankel Grade was used to evaluate function before and after treatment. Furthermore, the information of C(1)-C(2) bony fusion, cervical spine alignment, angle of sagittal curvature, and instability of the subaxial spine were collected from all patients preoperatively, immediately postoperatively and during follow-up period. All 21 patients had regular follow-up with an average duration of 96.4 months (range, 65 to 127 months). All children had good bony fusion within 6 months after treatment. There were 9 patients with lordotic alignment and 12 patients with straight alignment before surgery. After surgery, there were 12 patients with lordotic alignment and 9 patients with straight alignment. At the time of the last follow-up, 17 patients had lordotic alignment and 4 patients had straight alignment. No difference was found between pre- and post-operation (=0.354). The same result was found between post-operation and last follow-up (=0.095). Neither kyphotic nor swan-neck deformity was found in any of the 21 patients. The mean angle of sagittal curvature decreased from 31.7°±4.3°preoperatively to 15.5°±2.5°postoperatively (<0.001). The mean angle of sagittal curvature increased from 15.5°±2.5°postoperatively to 19.1°±2.7°at the final follow-up (=0.343). No spinal deformities or subaxial instabilities were found. Of the four patients with preoperative neurological defects, Frankel Grade was significantly improved at 3 months follow-up compared with pretreatment values. None of the patients experienced worsening neurological symptoms or injury to the vertebral artery. The results demonstrate that C(1)-C(2) pedicle screw fixation could achieve satisfactory clinical effects for the management of pediatric atlantoaxial dislocation with long-term follow-up.
探讨C(1)-C(2)椎弓根螺钉固定治疗小儿寰枢椎脱位的长期临床疗效。2005年3月至2011年4月,共纳入12例男性和9例女性患者,年龄3至9岁(平均6.1岁)。其中,14例(67%)为Ⅰ型寰枢椎不稳定脱位,7例(33%)为Ⅱ型可复性寰枢椎脱位。21例小儿寰枢椎脱位患者均接受了后路椎弓根螺钉固定术。采用Frankel分级评估治疗前后的功能。此外,收集所有患者术前、术后即刻及随访期间C(1)-C(2)骨融合、颈椎排列、矢状面弯曲角度及下颈椎不稳定的信息。21例患者均进行了定期随访,平均随访时间为96.4个月(范围65至127个月)。所有患儿在治疗后6个月内均获得了良好的骨融合。术前有9例患者颈椎前凸,12例患者颈椎变直。术后有12例患者颈椎前凸,9例患者颈椎变直。在最后一次随访时,17例患者颈椎前凸,4例患者颈椎变直。术前与术后比较差异无统计学意义(=0.354)。术后与最后一次随访比较结果相同(=0.095)。21例患者均未出现后凸或鹅颈畸形。矢状面弯曲平均角度术前为31.7°±4.3°,术后降至15.5°±2.5°(<0.001)。矢状面弯曲平均角度术后为15.5°±2.5°,最终随访时升至19.1°±2.7°(=0.343)。未发现脊柱畸形或下颈椎不稳定。4例术前有神经功能缺损的患者,随访3个月时Frankel分级较术前明显改善。所有患者均未出现神经症状恶化或椎动脉损伤。结果表明,C(1)-C(2)椎弓根螺钉固定治疗小儿寰枢椎脱位可获得满意的临床效果,并具有长期随访结果。