Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC, USA.
Gynecol Oncol. 2018 Jun;149(3):598-604. doi: 10.1016/j.ygyno.2018.01.035. Epub 2018 Feb 9.
Mucinous ovarian carcinomas (MOCs) are an uncommon subset of epithelial neoplasms, both clinically and molecularly distinct from other ovarian cancers. Pathologic diagnosis proves challenging, and metastatic disease from other sites-especially the digestive tract-must be excluded. Fortunately, most patients are diagnosed at an early stage of disease and often present with large, unilateral adnexal masses. Survival for patients with stage IA disease approaches over 90%, and surgery alone is sufficient. Patients with stage IB-II disease should receive adjuvant treatment but the specific regimen is controversial. In the following review, we provide an overview of mucinous ovarian carcinomas, with a particular focus on the treatment of patients with early stage disease.
黏液性卵巢癌(MOC)是上皮性肿瘤中一种罕见的亚型,在临床和分子上均有别于其他卵巢癌。病理诊断具有挑战性,必须排除来自其他部位的转移性疾病,尤其是消化道。幸运的是,大多数患者在疾病的早期阶段被诊断出来,并且常常表现为单侧附件的大肿块。IA 期疾病患者的生存率接近 90%,单独手术即可。IB-II 期疾病患者应接受辅助治疗,但具体方案存在争议。在以下综述中,我们将概述黏液性卵巢癌,特别关注早期疾病患者的治疗。