Angelini P, Heibig J, Leachman D R
Am J Cardiol. 1986 Aug 1;58(3):252-5. doi: 10.1016/0002-9149(86)90057-3.
During percutaneous transluminal coronary angioplasty (PTCA), the ability to maintain balloon inflations for 3 to 5 minutes, as opposed to the usual 30 to 60 seconds, may lead to improved early and late results. To determine the feasibility and clarify the advantages of distal hemoperfusion during PTCA, blood from the renal vein was manually sampled and then reinjected through the pressure port of the coronary balloon catheter during sustained balloon inflations in 3 patients. By supplying the periphery of the left anterior descending coronary artery with flows of 30 to 50 ml/min, ischemic manifestations were suppressed in all 3 cases. Hemoperfusion was performed without complications for as long as 5 minutes, using a maximum of 225 ml of blood. This new technique represents a major step toward the long-sought goal of extracorporeal coronary circulation during PTCA.
在经皮腔内冠状动脉成形术（PTCA）期间，与通常的30至60秒相比，能够将球囊充盈维持3至5分钟可能会改善早期和晚期结果。为了确定PTCA期间远端血液灌注的可行性并阐明其优势，在3例患者持续球囊充盈期间，手动采集肾静脉血液，然后通过冠状动脉球囊导管的压力端口重新注入。通过以30至50毫升/分钟的流速向左前降支冠状动脉周围供血，所有3例患者的缺血表现均得到抑制。使用最多225毫升血液进行了长达5分钟的无并发症血液灌注。这项新技术朝着PTCA期间体外冠状动脉循环这一长期追求的目标迈出了重要一步。
