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皮肤淋巴管周围萎缩。病灶内注射类固醇的一种不良副作用。

Perilymphatic atrophy of skin. An adverse side effect of intralesional steroid injections.

作者信息

Kravette M A

出版信息

Clin Podiatr Med Surg. 1986 Jul;3(3):457-62.

PMID:2943393
Abstract

A less frequently reported adverse side effect of local steroid injections has been described. Perilymphatic atrophy results in atrophy of the dermal structures and depigmentation along the course of the lymphatic vessels draining the site of injection. The five cases reported here all occurred in dark-skinned patients. Three of the five cases (Cases Three to Five) resolved spontaneously, the longest taking 9 months from the time of injection. The outcome of two of the patients (Cases One and Two) remain unknown since the patients were lost to follow-up. This report did not form any conclusions from the material reported here, but simply sought to make practitioners aware of the occurrence of this adverse side effect.

摘要

局部类固醇注射一种较少被报道的不良副作用已被描述。淋巴管周围萎缩导致皮肤结构萎缩以及沿注射部位引流的淋巴管走行出现色素脱失。此处报告的5例均发生在深色皮肤患者中。5例中的3例(病例三至五)自行缓解,最长从注射时起9个月。由于患者失访,另外2例患者(病例一和二)的结局未知。本报告并未从这里报道的材料得出任何结论,而只是试图让从业者知晓这种不良副作用的发生。

相似文献

1
Perilymphatic atrophy of skin. An adverse side effect of intralesional steroid injections.皮肤淋巴管周围萎缩。病灶内注射类固醇的一种不良副作用。
Clin Podiatr Med Surg. 1986 Jul;3(3):457-62.
2
Perilymphatic subcutaneous atrophy in adnexal hemangioma: a complication of intralesional corticosteroid injection.
Ophthalmic Surg. 1990 Mar;21(3):215-7.
3
Cutaneous atrophy after corticosteroid injection.皮质类固醇注射后的皮肤萎缩
Am Fam Physician. 1986 Jan;33(1):183-6.
4
Undesirable side effects following intralesional corticosteroid therapy.病灶内注射皮质类固醇治疗后的不良副作用。
Calif Med. 1972 Jan;116(1):55.
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Cutaneous foot depigmentation following an intra-articular steroid injection.
J Am Podiatr Med Assoc. 1991 Nov;81(11):606-7. doi: 10.7547/87507315-81-11-606.
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Cheiralgia paresthetica and linear atrophy as a complication of local steroid injection.感觉异常性手痛和线性萎缩作为局部类固醇注射的并发症
Arch Phys Med Rehabil. 1985 Sep;66(9):637-9.
7
Interdigital neuroma. Local cutaneous changes after corticosteroid injection.趾间神经瘤。皮质类固醇注射后的局部皮肤变化。
Clin Orthop Relat Res. 1995 Aug(317):185-7.
8
[An iatrogenic complication subsequent to an injection of corticoids into the instep].[向脚背注射皮质类固醇后的医源性并发症]
Phlebologie. 1986 Jul-Sep;39(3):527-37.
9
Steroid-induced skin changes following local injection.
Clin Orthop Relat Res. 1972 Sep;87:254-6.
10
Perilymphatic atrophy of the skin. A side effect of topical corticosteroid injection therapy.皮肤淋巴管周围萎缩。局部皮质类固醇注射治疗的一种副作用。
Arch Dermatol. 1974 Apr;109(4):558-9.

引用本文的文献

1
Septic and aseptic complications of corticosteroid injections: an assessment of 278 cases reviewed by expert commissions and mediation boards from 2005 to 2009.皮质类固醇注射的感染性和无菌性并发症:2005 年至 2009 年专家委员会和调解委员会审查的 278 例评估。
Dtsch Arztebl Int. 2012 Jun;109(24):425-30. doi: 10.3238/arztebl.2012.0425. Epub 2012 Jun 15.
2
Predicting drug side-effect profiles: a chemical fragment-based approach.预测药物副作用谱:基于化学片段的方法。
BMC Bioinformatics. 2011 May 18;12:169. doi: 10.1186/1471-2105-12-169.
3
Adverse effects of extra-articular corticosteroid injections: a systematic review.
关节外皮质类固醇注射的不良反应:系统评价。
BMC Musculoskelet Disord. 2010 Sep 13;11:206. doi: 10.1186/1471-2474-11-206.