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阴道解剖植入物在盆腔器官脱垂中的长期随访。

Long term Follow-up of Transvaginal Anatomical Implant of Mesh in Pelvic organ prolapse.

机构信息

Department of Urology, West China Hospital, Sichuan University, Chengdu, China.

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Sci Rep. 2018 Feb 12;8(1):2829. doi: 10.1038/s41598-018-21090-w.

DOI:10.1038/s41598-018-21090-w
PMID:29434209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5809369/
Abstract

Transvaginal mesh (TVM) is a minimally invasive but effective treatment for pelvic organ prolapse (POP). However, mesh exposure is a common and problematic complication after TVM. This study assessed the safety and long-term outcomes of TVM. A retrospective review was performed on the medical records of 175 consecutive patients who underwent TVM with the anatomical implant technique for pelvic organ prolapse at our center from April 2007 to December 2012. All operations were performed using TVM with the anatomical implant technique. Intraoperative variables, postoperative complications, and TVM outcomes were assessed. In average of 8 years (ranging from 4 to 10 years), the objective cure ratio reached 99.4%; and the subjective success rate of the TVM operation was 91.4%. Only 2 cases (1.1%) were identified as having mesh exposure. The reoperation rate was 4.0% (95% CI, 1.1-6.9%). No patients abstained from sex due to the operation or postoperative discomfort. Our anatomical implant technique for correcting POP is feasible in TVM procedures, which lead to favourable subjective and objective outcomes with the lowest rates of mesh exposure (1.1%) in published data. Therefore, performing TVM operations with the appropriate technique could consider to be permitted.

摘要

经阴道网片(TVM)是治疗盆腔器官脱垂(POP)的一种微创但有效的方法。然而,网片暴露是 TVM 后常见且棘手的并发症。本研究评估了 TVM 的安全性和长期疗效。我们对 2007 年 4 月至 2012 年 12 月期间在我中心接受 TVM 解剖植入技术治疗盆腔器官脱垂的 175 例连续患者的病历进行了回顾性分析。所有手术均采用 TVM 解剖植入技术进行。评估了术中变量、术后并发症和 TVM 结果。平均随访 8 年(4-10 年),客观治愈率达到 99.4%;TVM 手术的主观成功率为 91.4%。仅 2 例(1.1%)发生网片暴露。再次手术率为 4.0%(95%CI,1.1-6.9%)。没有患者因手术或术后不适而避免性生活。我们的 TVM 解剖植入技术治疗 POP 是可行的,与已发表数据中最低的网片暴露率(1.1%)相比,可获得良好的主观和客观疗效。因此,采用适当的技术进行 TVM 手术是可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9c/5809369/e15a92a7af85/41598_2018_21090_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9c/5809369/e7a45d1444f7/41598_2018_21090_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9c/5809369/0c8a7f3cf8f2/41598_2018_21090_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9c/5809369/e15a92a7af85/41598_2018_21090_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9c/5809369/e7a45d1444f7/41598_2018_21090_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9c/5809369/0c8a7f3cf8f2/41598_2018_21090_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9c/5809369/e15a92a7af85/41598_2018_21090_Fig3_HTML.jpg

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本文引用的文献

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Changes in elastin density in different locations of the vaginal wall in women with pelvic organ prolapse.盆腔器官脱垂女性阴道壁不同位置弹性蛋白密度的变化
Int Urogynecol J. 2014 Dec;25(12):1673-81. doi: 10.1007/s00192-014-2431-9. Epub 2014 May 28.
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Complications of pelvic organ prolapse surgery and methods of prevention.盆腔器官脱垂手术的并发症及预防方法。
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Use of a visual analog scale for evaluation of bother from pelvic organ prolapse.使用视觉模拟量表评估盆腔器官脱垂的困扰程度。
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Medium-term clinical outcomes following surgical repair for vaginal prolapse with tension-free mesh and vaginal support device.使用无张力网片和阴道支撑装置手术修复阴道脱垂后的中期临床结果。
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