Rittschof Clare C, Hughes Kimberly A
Department of Entomology, University of Kentucky, Lexington, KY, 40546, USA.
Department of Biological Sciences, Florida State University, Tallahassee, FL, 32306, USA.
Nat Commun. 2018 Feb 12;9(1):489. doi: 10.1038/s41467-018-02971-0.
Animal behavioural traits often covary with gene expression, pointing towards a genomic constraint on organismal responses to environmental cues. This pattern highlights a gap in our understanding of the time course of environmentally responsive gene expression, and moreover, how these dynamics are regulated. Advances in behavioural genomics explore how gene expression dynamics are correlated with behavioural traits that range from stable to highly labile. We consider the idea that certain genomic regulatory mechanisms may predict the timescale of an environmental effect on behaviour. This temporally minded approach could inform both organismal and evolutionary questions ranging from the remediation of early life social trauma to understanding the evolution of trait plasticity.
动物行为特征常常与基因表达共同变化，这表明基因组对生物体对环境线索的反应存在限制。这种模式凸显了我们在理解环境响应性基因表达的时间进程方面的差距，此外，还凸显了这些动态过程是如何受到调控的。行为基因组学的进展探索了基因表达动态与从稳定到高度不稳定的行为特征之间的相关性。我们考虑这样一种观点，即某些基因组调控机制可能预测环境对行为影响的时间尺度。这种具有时间意识的方法可以为从早期生活社会创伤的修复到理解性状可塑性的进化等生物体和进化问题提供信息。
