Hadchiti Joya, Kamar Francois G, Ghosn Jean Abi, Haidar Mohamad, Younes Ahmad, Obeid Antoine, Haddad Marwan, Farhat Fadi, Chehade Feras
Faculty of Medical Science, Lebanese University, Hadas, Lebanon.
Department of Oncology, Mount Lebanon Hospital, Beirut, Lebanon.
Mol Clin Oncol. 2018 Feb;8(2):236-241. doi: 10.3892/mco.2017.1507. Epub 2017 Nov 21.
Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, commonly involves the lymph nodes but may secondarily involve the skin. Purely cutaneous disease without lymphatics or internal organ involvement occurs rarely. The present report detailed a rare case of F-fluoro-2-deoxyglucose positron emission-computed tomography (FDG PET-CT) performed in a 33-year-old male soldier with a purely cutaneous form of RDD. Staging with FDG PET-CT was ordered prior to excisional biopsies of the aforedescribed masses and pathology reported RDD. The case demonstrated accurate localization of increased radioglucose metabolism. The present case was also discussed in light of literature data in terms of clinical features, etiologies, histology, medical imaging, therapy planning and prognosis.
罗萨伊-多夫曼病（RDD），即伴巨大淋巴结病的窦性组织细胞增多症，通常累及淋巴结，但也可能继发累及皮肤。极少发生无淋巴管或内脏器官受累的单纯皮肤病变。本报告详细介绍了一例罕见的F-氟-2-脱氧葡萄糖正电子发射计算机断层扫描（FDG PET-CT），该检查是在一名33岁患有单纯皮肤型RDD的男性士兵身上进行的。在对上述肿物进行切除活检之前，进行了FDG PET-CT分期，病理报告为RDD。该病例显示了放射性葡萄糖代谢增加的准确定位。还根据文献数据，从临床特征、病因、组织学、医学影像学、治疗规划和预后等方面对本病例进行了讨论。
