Rasche H, Meier C R, Schneider J, Gröticke J, Schönhöfer P
Dtsch Med Wochenschr. 1986 Sep 12;111(37):1406-7. doi: 10.1055/s-2008-1068642.
Seventeen oncological patients reported unpleasant but clinically harmless skin sensations directly after intravenous injection of dexamethasone, persisting for 2-4 minutes. In 16 cases, these paraesthesias (tingling, burning, itching, twinging) occurred in the genital or perineal area. In one case, the symptoms started in this area and then extended over the entire truncus integument for a short period. The cause of this obviously drug-induced side effect is unknown.
17名肿瘤患者在静脉注射地塞米松后直接报告了不愉快但临床上无害的皮肤感觉,持续2至4分钟。16例中,这些感觉异常(刺痛、灼痛、瘙痒、刺痛)出现在生殖器或会阴区域。1例中,症状始于该区域,然后在短时间内扩展至整个躯干皮肤。这种明显由药物引起的副作用的原因尚不清楚。