Marčić Marino, Marčić Ljiljana, Titlić Marina
Department of Neurology, Clinical Hospital Center Split, Split, Croatia.
Department of Radiology, Clinical Hospital Center Split, Split, Croatia.
Acta Med Iran. 2018 Jan;56(1):62-66.
Kleine-Levin syndrome (KLS) is a rare sleep disorder mainly affecting teenage boys in which the main features are intermittent hypersomnolence, behavioral and cognitive disturbances, hyperphagia, and in some cases hyper sexuality. Etiology is unknown, and there is no specific clinical or imaging test for this syndrome even though the illness has well-defined clinical features. Also, there is no effective treatment for KLS. KLS is self-limited, so the prognosis for these patients is not so bad. This study presents our case report and comprehensive workout that led to diagnosis which is primarily clinical. Our patient is a 20-year-old man referred to our clinic because of sleeping problems. At the age of 14, he presented with complaints of the excessive duration of sleep, increased appetite, excessive daytime sleepiness, loss of interest in social activities during attendance of high school and hallucinations. The excessive diagnostic procedure does not find pathological. Kleine-Levin syndrome (KLS) is a rare sleep disorder of unknown etiology which diagnosis is clinical and diagnostic workup is mainly to exclude other similar conditions. There is no specific therapy, but the disease is self-limited and with good prognosis.
克莱恩-莱文综合征（KLS）是一种罕见的睡眠障碍，主要影响青少年男性，其主要特征为间歇性嗜睡、行为和认知障碍、食欲亢进，在某些情况下还会出现性欲亢进。病因不明，尽管该疾病具有明确的临床特征，但尚无针对此综合征的特异性临床或影像学检查。此外，目前尚无治疗KLS的有效方法。KLS具有自限性，因此这些患者的预后并非很差。本研究展示了我们的病例报告以及最终主要通过临床诊断得出结论的全面诊断过程。我们的患者是一名20岁男性，因睡眠问题前来我们诊所就诊。14岁时，他出现了睡眠时间过长、食欲增加、日间过度嗜睡、在高中就读期间对社交活动失去兴趣以及幻觉等症状。经过大量诊断检查未发现病理性问题。克莱恩-莱文综合征（KLS）是一种病因不明的罕见睡眠障碍，其诊断依靠临床判断，诊断检查主要是排除其他类似病症。目前尚无特异性治疗方法，但该疾病具有自限性且预后良好。
