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高热伴皮疹的青少年男性:我们可能遗漏了什么?

Teenage boy with high fever and rash: what could we be missing?

作者信息

Oliveira Gracinda Nogueira, Costa Sofia, Costa Filipa Dias, Dionísio Teresa, Carvalho Leonor

机构信息

Department of Paediatrics, Hospital Pediátrico de Coimbra, Coimbra, Portugal.

Paediatric Intensive Care Unit, Hospital Pediátrico de Coimbra, Coimbra, Portugal.

出版信息

BMJ Case Rep. 2018 Feb 8;2018:bcr-2017-223497. doi: 10.1136/bcr-2017-223497.

DOI:10.1136/bcr-2017-223497
PMID:29437816
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5836690/
Abstract

A 15-year-old boy was admitted to a local hospital with high fever, generalised rash and a mild sore throat. He was started on intravenous flucloxacillin and 12 hours later develops a sustained low diastolic blood pressure (DBP), unresponsive to fluid volume expansion and cardiovascular support with dopamine. Intravenous clindamycin was added and transportation to paediatric intensive care unit arranged. Dopamine dosing was increased and norepinephrine infusion was added subsequently with immediate stabilisation of DBP. A sacrococcygeal pilonidal abscess was identified, requiring prompt surgical drainage. The microbiological culture of abscess material was positive for an enterotoxin-producing He was free of symptoms after 4 days. This case report summarises a potential severe complication of the pilonidal disease.

摘要

一名15岁男孩因高热、全身性皮疹和轻度咽痛入住当地医院。他开始接受静脉注射氟氯西林治疗,12小时后出现持续性低舒张压(DBP),对液体量扩充和多巴胺的心血管支持无反应。加用静脉注射克林霉素,并安排转运至儿科重症监护病房。增加多巴胺剂量,随后加用去甲肾上腺素输注,DBP立即稳定。发现骶尾部藏毛窦脓肿,需要立即进行手术引流。脓肿材料的微生物培养显示产肠毒素的[具体细菌名称未给出]呈阳性。4天后他症状消失。本病例报告总结了藏毛疾病的一种潜在严重并发症。

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本文引用的文献

1
[Puberty is a major factor in pilonidal sinus disease : Gender-specific investigations of case number development in Germany from 2007 until 2015].[青春期是藏毛窦疾病的一个主要因素:2007年至2015年德国病例数发展的性别特异性调查]
Chirurg. 2017 Nov;88(11):961-967. doi: 10.1007/s00104-017-0463-7.
2
Novel Approaches in Pilonidal Sinus Treatment.藏毛窦治疗的新方法。
Prague Med Rep. 2016;117(4):145-152. doi: 10.14712/23362936.2016.15.
3
Does Sacrococcygeal Angle Play a Role on Pilonidal Sinus Etiology?骶尾角在藏毛窦病因学中起作用吗?
Prague Med Rep. 2015;116(3):219-24. doi: 10.14712/23362936.2015.61.
4
Microbiology of the infected recurrent sacrococcygeal pilonidal sinus.感染性复发性骶尾部藏毛窦的微生物学
Int Wound J. 2016 Apr;13(2):231-7. doi: 10.1111/iwj.12274. Epub 2014 Apr 24.
5
Practice parameters for the management of pilonidal disease.藏毛疾病管理的实践参数。
Dis Colon Rectum. 2013 Sep;56(9):1021-7. doi: 10.1097/DCR.0b013e31829d2616.
6
Intermammary pilonidal sinus.乳房间藏毛窦
Int J Trichology. 2010 Jul;2(2):116-8. doi: 10.4103/0974-7753.77526.
7
Persistence survey of toxic shock syndrome toxin-1 producing Staphylococcus aureus and serum antibodies to this superantigen in five groups of menstruating women.五组月经期妇女中毒性休克综合征毒素 1 产生金黄色葡萄球菌的持续感染调查和对这种超抗原的血清抗体。
BMC Infect Dis. 2010 Aug 23;10:249. doi: 10.1186/1471-2334-10-249.
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Pilonidal disease.藏毛疾病
Surg Clin North Am. 2002 Dec;82(6):1169-85. doi: 10.1016/s0039-6109(02)00062-2.
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Cutaneous manifestations in childhood staphylococcal sepsis.儿童葡萄球菌败血症的皮肤表现
J Dermatol. 2002 Jan;29(1):43-5. doi: 10.1111/j.1346-8138.2002.tb00164.x.
10
Bacteremic nonmenstrual staphylococcal toxic shock syndrome associated with enterotoxins A and C.与A和C型肠毒素相关的非月经性葡萄球菌菌血症性中毒性休克综合征
Clin Infect Dis. 2001 Feb 1;32(3):E53-6. doi: 10.1086/318494. Epub 2001 Jan 24.