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小口径血管移植物为何失败:临床与实验经验综述及界面处血液相互作用的意义

Why small caliber vascular grafts fail: a review of clinical and experimental experience and the significance of the interaction of blood at the interface.

作者信息

Esquivel C O, Blaisdell F W

出版信息

J Surg Res. 1986 Jul;41(1):1-15. doi: 10.1016/0022-4804(86)90002-8.

DOI:10.1016/0022-4804(86)90002-8
PMID:2943940
Abstract

The results using polytetrafluoroethylene (PTFE) and tanned human umbilical cord vein (HUV) grafts are discussed. These two grafts perform well for reconstructions above the knee and the results are similar to the autogenous saphenous vein (ASV) grafts in several series; however, in more distal reconstructions the PTFE and HUV are far inferior to ASV grafts. The factors responsible for graft failure including the events which take place at the blood interface are reviewed. New material surfaces under investigation such as degradable grafts, heparin-bonded surfaces, and endothelial-seeded fabrics are also addressed.

摘要

讨论了使用聚四氟乙烯(PTFE)和鞣制人脐静脉(HUV)移植物的结果。这两种移植物在膝上重建中表现良好,在几个系列中的结果与自体隐静脉(ASV)移植物相似;然而,在更远端的重建中,PTFE和HUV远不如ASV移植物。回顾了导致移植物失败的因素,包括在血液界面发生的事件。还讨论了正在研究的新材料表面,如可降解移植物、肝素结合表面和内皮种植织物。

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