OrthoCarolina Hip and Knee Center, Charlotte, NC; Department of Orthopaedics, University of Utah, Salt Lake City, UT.
Orthopaedic Surgery at Rush University Medical Center, Chicago, IL.
J Arthroplasty. 2018 Jun;33(6):1879-1883. doi: 10.1016/j.arth.2018.01.022. Epub 2018 Jan 31.
Patients presenting with both chronic periprosthetic joint infection (PJI) and extensor mechanism disruption (EMD) pose a significant challenge. As there is little in the literature regarding outcomes of patients with concomitant PJI and EMD, we performed a multicenter study to evaluate the outcomes.
Sixty patients with concomitant diagnoses of PJI and EMD were evaluated from 5 institutions. Patient demographics, presentation type, surgical management, and outcomes including recurrent infections, final surgery, and ambulatory status were documented.
Fifty-three of 60 patients had an attempted extensor mechanism reconstruction/repair (EMR) of which 12 (23%) were successful, averaging 3.5 (range, 2-7) intervening surgeries. Forty-one patients (77%) were considered failures with recurrence of infection as most common failure (80%); 26 ended in fusion, 10 in above knee amputation, 3 with chronic resection arthroplasty, and 2 with chronic spacers/EMD. Seven patients had no attempt at EMR but proceeded directly to fusion (n = 6) or amputation (n = 1). There was no statistical difference between groups that had success or failure of EMR in age, American Society of Anesthesiologists Physical Status Classification System, or body mass index.
Our study demonstrates that concomitant EMD and PJI is a dreaded combination with poor outcomes regardless of treatment. Eradication of infection and reconstruction of the extensor mechanism often require numerous surgeries and despite great effort often end in failure. Consideration of early fusion or amputation may be preferable in some patients to avoid the morbidity and mortality of repeated surgeries.
同时患有慢性假体周围关节感染(PJI)和伸肌机制破坏(EMD)的患者带来了巨大的挑战。由于文献中关于同时患有 PJI 和 EMD 的患者的结果的内容很少,我们进行了一项多中心研究来评估这些结果。
从 5 家机构评估了 60 例同时诊断为 PJI 和 EMD 的患者。记录了患者的人口统计学、表现类型、手术管理以及包括复发性感染、最终手术和步行状态在内的结果。
在 60 例患者中,有 53 例尝试了伸肌机制重建/修复(EMR),其中 12 例(23%)成功,平均进行了 3.5 次(范围 2-7 次)介入手术。41 例(77%)被认为是失败的,最常见的失败原因是感染复发(80%);26 例最终融合,10 例膝关节以上截肢,3 例慢性切除关节成形术,2 例慢性间隔物/EMD。有 7 例患者未尝试 EMR,而是直接进行融合(n=6)或截肢(n=1)。在 EMR 成功或失败的患者中,年龄、美国麻醉医师协会身体状况分类系统或体重指数均无统计学差异。
我们的研究表明,同时患有 EMD 和 PJI 是一种可怕的组合,无论治疗如何,结果都很差。消除感染和重建伸肌机制通常需要多次手术,尽管付出了巨大努力,但往往以失败告终。在某些患者中,考虑早期融合或截肢可能比反复手术更可取,以避免多次手术的发病率和死亡率。