Kremer Hovinga T K, de Jong P E, de Zeeuw D, Donker A J, Schuur K H, van der Hem G K
Nephron. 1986;44 Suppl 1:64-7. doi: 10.1159/000184050.
We studied the frequency of restenosis and the effects of percutaneous transluminal renal angioplasty (PTRA) on blood pressure (BP) and particularly on renal function in all patients in whom successful dilatation was performed. Restenosis was found in 42% of the patients with an atherosclerotic renal artery stenosis and in 22% of the patients with fibromuscular dysplasia. BP improvement was seen in 70-80% of the patients with unilateral stenosis or with successful bilateral dilatation (group I) whereas only seldom was an effect on BP observed in patients with more complicated disease, such as those with an occlusion of the contralateral artery (group II). Remarkably, however, both in group I and in group II, in about half of the patients an improvement in renal function was found, even 2-3 years after the procedure. Our results thus indicate that PTRA can be useful in preservation or even improvement of renal function, even if no effect on blood pressure can be expected.
我们研究了所有成功进行扩张术患者的再狭窄发生率以及经皮腔内肾血管成形术（PTRA）对血压（BP）尤其是肾功能的影响。在患有动脉粥样硬化性肾动脉狭窄的患者中，42%出现了再狭窄；在患有纤维肌发育异常的患者中，22%出现了再狭窄。单侧狭窄或双侧扩张成功的患者（I组）中，70 - 80%的患者血压得到改善，而在患有更复杂疾病的患者中，如对侧动脉闭塞的患者（II组），很少观察到血压有变化。然而，值得注意的是，无论是I组还是II组，约半数患者的肾功能都有改善，甚至在术后2至3年仍有改善。因此，我们的结果表明，即使预期对血压没有影响，PTRA在保存甚至改善肾功能方面可能是有用的。
