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眼球表面复合性软骨迷离瘤:一组独特的临床病理病例系列及文献综述

Epibulbar complex cartilaginous choristoma: A distinctive clinicopathological case series and literature review.

作者信息

Zhang Zongduan, Yang Zhengwei, Pan Qintuo, Qin Xiaoyi, Deng Yuxuan, Cao Yuehong

机构信息

Jinhua Eye Hospital, Jinhua, ZheJiang Eye Hospital of Wenzhou Medical University, Wenzhou, China.

出版信息

Medicine (Baltimore). 2018 Feb;97(7):e9902. doi: 10.1097/MD.0000000000009902.

Abstract

To newly describe the clinical and histopathological characteristics of epibulbar complex cartilaginous choristoma incidentally observed in a series of pterygium excision patients.Noncomparative case series with chart review of 8 patients.During a 4-year period, we identified 8 cases of conventional unilateral nasal subpterygial cartilaginous choristoma in 1799 pterygium patients and analyzed their clinicopathological features. The incidence rate of this entity is 0.44% in pterygium patients. All of the cartilaginous choristomas were buried deep in the caruncle, covered by the pterygium, and embedded in tenon facia tissue. Its clinicopathological characteristics include hyaline cartilaginous tissue that is surrounded by fibrous connective tissue and smooth muscle bundles. S-100 protein-staining specifically revealed chondrocytes embedded within chondroid matrix.Epibulbar complex cartilaginous choristoma covered by pterygia and predominantly observed in the older population is rare. The lesions were buried deep in the caruncle, covered by the pterygium and embedded in tenon fascia tissue. These findings are inconsistent with those in previous reports.

摘要

为全新描述在一系列翼状胬肉切除患者中偶然发现的眼球表面复合性软骨迷离瘤的临床和组织病理学特征。对8例患者进行图表回顾的非对照病例系列研究。在4年期间,我们在1799例翼状胬肉患者中识别出8例传统单侧鼻侧翼状胬肉下软骨迷离瘤,并分析了其临床病理特征。该病变在翼状胬肉患者中的发生率为0.44%。所有软骨迷离瘤均深埋于泪阜,被翼状胬肉覆盖,并包埋于眼球筋膜组织中。其临床病理特征包括被纤维结缔组织和平滑肌束包绕的透明软骨组织。S-100蛋白染色特异性显示软骨样基质内包埋的软骨细胞。被翼状胬肉覆盖且主要见于老年人群的眼球表面复合性软骨迷离瘤罕见。病变深埋于泪阜,被翼状胬肉覆盖并包埋于眼球筋膜组织中。这些发现与既往报道不一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26d0/5839851/66a4f55320c6/medi-97-e9902-g001.jpg

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