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阿塔卡马沙漠中放线菌的天然产物多样性。

Natural product diversity of actinobacteria in the Atacama Desert.

作者信息

Rateb Mostafa E, Ebel Rainer, Jaspars Marcel

机构信息

School of Science & Sport, University of the West of Scotland, Paisley, PA1 2BE, UK.

Marine Biodiscovery Centre, University of Aberdeen, Aberdeen, AB24 3UE, UK.

出版信息

Antonie Van Leeuwenhoek. 2018 Aug;111(8):1467-1477. doi: 10.1007/s10482-018-1030-z. Epub 2018 Feb 14.

Abstract

The Atacama Desert of northern Chile is considered one of the most arid and extreme environment on Earth. Its core region was described as featuring "Mars-like" soils that were at one point deemed too extreme for life to exist. However, recent investigations confirmed the presence of diverse culturable actinobacteria. In the current review, we discuss a total of 46 natural products isolated to date representing diverse chemical classes characterized from different actinobacteria isolated from various locations in the Atacama Desert. Their reported biological activities are also discussed.

摘要

智利北部的阿塔卡马沙漠被认为是地球上最干旱、最极端的环境之一。其核心区域被描述为具有“类火星”土壤,这些土壤一度被认为过于极端,生命无法存在。然而,最近的调查证实了多种可培养放线菌的存在。在当前的综述中,我们讨论了迄今为止从阿塔卡马沙漠不同地点分离出的不同放线菌中鉴定出的总共46种天然产物,它们代表了不同的化学类别。还讨论了它们已报道的生物活性。

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