Roxanas Milton G
Asssociate Professor of Psychiatry, Sydney Adventist Medical School, University of Sydney, Sydney, NSW, Australia.
Australas Psychiatry. 2018 Oct;26(5):520-523. doi: 10.1177/1039856218758566. Epub 2018 Feb 15.
The aims of this study are to describe two patients whose manic symptoms persisted for several months after the cessation of corticosteroids, to review the literature and to suggest treatment.
The presentation of two elderly patients with persistent manic symptoms following cessation of corticosteroids several months previously afforded the author the opportunity to examine them carefully, investigate and treat them.
The patients were investigated to rule out other causes and were treated with sodium valproate and quetiapine (in the second patient). When well, the medications were slowly decreased and stopped. Both patients were well at one-year follow-up.
Manic symptoms may persist for many months after stopping corticosteroids and active treatment is needed to control them.
本研究旨在描述两名患者，其躁狂症状在停用皮质类固醇激素后持续数月，回顾相关文献并提出治疗建议。
两名老年患者在数月前停用皮质类固醇激素后出现持续躁狂症状，作者有机会对他们进行仔细检查、调查和治疗。
对患者进行检查以排除其他病因，给予丙戊酸钠治疗（第二名患者还使用了喹硫平）。病情好转后，逐渐减少并停用药物。两名患者在一年随访时情况良好。
停用皮质类固醇激素后，躁狂症状可能持续数月，需要积极治疗以控制症状。
