1 Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Wht 4-427, Boston, MA 02114.
AJR Am J Roentgenol. 2018 Apr;210(4):866-868. doi: 10.2214/AJR.17.18801. Epub 2018 Feb 15.
We reviewed the safety of nuclear diuretic renography with furosemide in patients with sulfonamide allergies. The electronic health record was used to uncover any drug effects reported within 30 days of diuretic renograms performed between January 2009 and December 2015.
Eighty-three of 1103 (7.5%) diuretic renograms were performed on patients with sulfonamide allergies. Two instances of minor rash occurred. No serious reactions occurred. Furosemide is associated with an extremely low risk of minor reactions in patients with sulfonamide allergies.
我们回顾了在磺胺类药物过敏患者中使用呋塞米进行核利尿剂肾图检查的安全性。电子健康记录用于发现 2009 年 1 月至 2015 年 12 月期间进行利尿剂肾图检查后 30 天内报告的任何药物作用。
在 1103 例利尿剂肾图中,有 83 例(7.5%)在磺胺类药物过敏患者中进行。发生了 2 例轻微皮疹。未发生严重反应。在磺胺类药物过敏患者中,呋塞米与极小的不良反应风险相关。