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圈养普通狨猴(Callithrix jacchus)的25-羟基维生素D、甲状旁腺激素和血清钙水平:参考值及年龄、性别、季节和长骨骨骺闭合的影响

25-OH-vitamin D, parathyroid hormone, and calcium serum levels in captive common marmosets (Callithrix jacchus): Reference values and effect of age, sex, season, and closure of long bone epiphyses.

作者信息

Bosseler Leslie, Bakker Jaco, Duchateau Luc, Remarque Ed, Langermans Jan A M, Cornillie Pieter, Chiers Koen

机构信息

Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

Animal Science Department, Biomedical Primate Research Centre, Rijswijk, The Netherlands.

出版信息

J Med Primatol. 2018 Jun;47(3):172-177. doi: 10.1111/jmp.12334. Epub 2018 Feb 15.

DOI:10.1111/jmp.12334
PMID:29446837
Abstract

BACKGROUND

To date, reference values for 25-OH-vitamin D, parathyroid hormone (PTH), and calcium in serum of common marmosets (Callithrix jacchus) based on a large sample size are not available.

METHODS

Serum reference values for these parameters were determined and correlated with sex, age, season of sampling, and time of long bone epiphyseal closure in captive-housed marmosets.

RESULTS AND CONCLUSIONS

The 90% reference range for serum 25-OH-vitamin D is 47.40-370.4 nmol/L, for PTH 2.10-30.51 pmol/L, and for calcium 2.08-2.63 mmol/L. Lower levels of vitamin D were measured in fall compared with the other seasons. Levels of PTH were higher in males than in females, and calcium levels were lower in younger animals compared with older marmosets. No other effects of age, sex, season, or timing of growth plate closure were found.

摘要

背景

迄今为止,尚无基于大样本量的普通狨猴(Callithrix jacchus)血清中25-羟基维生素D、甲状旁腺激素(PTH)和钙的参考值。

方法

测定了圈养狨猴这些参数的血清参考值,并将其与性别、年龄、采样季节和长骨骨骺闭合时间进行关联。

结果与结论

血清25-羟基维生素D的90%参考范围为47.40 - 370.4 nmol/L,PTH为2.10 - 30.51 pmol/L,钙为2.08 - 2.63 mmol/L。与其他季节相比,秋季测得的维生素D水平较低。雄性的PTH水平高于雌性,幼年动物的钙水平低于老年狨猴。未发现年龄、性别、季节或生长板闭合时间的其他影响。

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