Christman Mitalee P, Sukhdeo Kumar, Kim Randie H, Meehan Shane, Rieder Evan, Sicco Kristen Lo, Franks Andrew
New York University Langone Health, New York.
Dermatol Online J. 2017 Dec 15;23(12):13030/qt3xp109qd.
Lichen myxedematosus is condition characterized by localized areas of dermal deposition of mucin, presenting with firm papules localized to few areas of the body. The condition needs to be excluded from scleromyxedema, which, in addition to the firm papular eruption, has areas of induration and is usually associated with a monoclonal gammopathyand systemic symptoms. We present a 62-year-old woman with a several-year history of asymptomatic, firm papules over the face and arms with no evidence of thyroid disease or a monoclonal gammopathy,which is consistent with a diagnosis of localized lichen myxedematosus, the discrete papular variant. The patient is being treated with a topical calcineurininhibitor.
黏液水肿性苔藓是一种以皮肤黏蛋白沉积局部区域为特征的疾病,表现为局限于身体少数部位的坚实丘疹。该疾病需要与硬化性黏液水肿相鉴别,硬化性黏液水肿除了有坚实的丘疹性皮疹外,还有硬结区域,通常与单克隆丙种球蛋白病及全身症状相关。我们报告一例62岁女性,有面部和手臂出现无症状坚实丘疹数年的病史,无甲状腺疾病或单克隆丙种球蛋白病的证据,符合局限性黏液水肿性苔藓(离散丘疹型)的诊断。患者正在接受外用钙调神经磷酸酶抑制剂治疗。