Magureanu Marineta, Stanila Adriana, Bunescu Liviu Valentin, Armeanu Cristina
"Ghencea Medical Center" Bucharest, Romania.
Research Center of Ocular Surface, "Lucian Blaga" University, Ophthalmology Clinic - RCOS, Sibiu, Romania.
Rom J Ophthalmol. 2016 Oct-Dec;60(4):237-248.
It is known that elevated intraocular pressure (IOP) is the primary risk factor for glaucoma. Recently, more and more evidences have shown that the vascular deficit also plays an important role in the pathogenesis and progressions of glaucomatous optic neuropathy. This issue is backed up by glaucomatous optic neuropathy (GON) cases drug compensated in which the progression of the disease in one or both eyes is ascertained despite a normal and relatively constant IOP. The present study evaluated the hemodynamic parameters in the retrobulbar circulation in patients with progressive glaucomatous optic neuropathy in one eye, who received compensated medication. The hemodynamic parameters (PSV, EDV, IR) were measured by using color Doppler ultrasound and progression was evaluated by a repeated automated perimetry. The obtained values were statistically analyzed and compared with those obtained for the stable eye.
众所周知，眼压升高是青光眼的主要危险因素。最近，越来越多的证据表明，血管缺陷在青光眼性视神经病变的发病机制和进展中也起着重要作用。这一问题得到了青光眼性视神经病变（GON）药物治疗病例的支持，在这些病例中，尽管眼压正常且相对稳定，但仍可确定一只或两只眼睛的疾病进展。本研究评估了单眼进行性青光眼性视神经病变患者在接受代偿性药物治疗时球后循环的血流动力学参数。使用彩色多普勒超声测量血流动力学参数（PSV、EDV、IR），并通过重复自动视野检查评估病情进展。对获得的值进行统计分析，并与健侧眼获得的值进行比较。
