Banou Lamprini, Dastiridou Anna, Giannoukas Athanasios, Kouvelos Georgios, Baros Christos, Androudi Sofia
Department of Ophthalmology, University of Thessaly, 41334 Larissa, Greece.
Department of Vascular Surgery, University of Thessaly, 41334 Larissa, Greece.
Diagnostics (Basel). 2023 Feb 5;13(4):588. doi: 10.3390/diagnostics13040588.
Glaucoma is a progressive optic neuropathy and one of the leading causes of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is the major risk factor for the onset and progression of glaucoma. In addition to elevated IOP, impaired intraocular blood flow is also considered to be involved in the pathogenesis of glaucoma. Various techniques have been used to assess ocular blood flow (OBF), including Color Doppler Imaging (CDI), a technique used in ophthalmology in recent decades. This article reviews the role of CDI in both the diagnosis and effective monitoring of glaucoma progression, presenting the protocol for imaging and its advantages, as well as the limitations of its use. Moreover, it analyzes the pathophysiology of glaucoma, focusing on vascular theory and its role in the onset and progression of the disease.
青光眼是一种进行性视神经病变，是全球不可逆性失明的主要原因之一。眼压升高是青光眼发病和进展的主要危险因素。除了眼压升高外，眼内血流受损也被认为与青光眼的发病机制有关。已经使用了各种技术来评估眼血流（OBF），包括彩色多普勒成像（CDI），这是近几十年来眼科使用的一种技术。本文综述了CDI在青光眼诊断和有效监测病情进展中的作用，介绍了成像方案及其优点，以及其使用的局限性。此外，还分析了青光眼的病理生理学，重点关注血管理论及其在疾病发病和进展中的作用。
