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八年国家早期关节炎队列研究中类风湿关节炎系统水平疗效指标的高依从性。

High Adherence to System-Level Performance Measures for Rheumatoid Arthritis in a National Early Arthritis Cohort Over Eight Years.

机构信息

University of Calgary, Calgary, Alberta, Canada, and Arthritis Research Canada, Richmond, British Columbia, Canada.

University of Toronto, Toronto, Ontario, Canada.

出版信息

Arthritis Care Res (Hoboken). 2018 Jun;70(6):842-850. doi: 10.1002/acr.23439. Epub 2018 Mar 25.

Abstract

OBJECTIVE

To assess adherence to 3 system-level performance measures in a national early rheumatoid arthritis (RA) cohort.

METHODS

Patients enrolled in the Canadian Early Arthritis Cohort (2007-2015) who met 1987 or 2010 American College of Rheumatology/European League Against Rheumatism criteria with <1 year of symptom duration and ≥1 year of followup after enrollment were included. Performance measures assessed were the percentage of RA patients seen in yearly followup, and the number of gaps between visits of >12 or >14 months, the percentage of RA patients treated with a disease-modifying antirheumatic drug (DMARD), and days from RA diagnosis to initiation of a DMARD. Results are shown stratified by enrollment year to assess for temporal changes in performance.

RESULTS

A total of 1,763 early RA patients were included (mean age 54 years, 73% female, and 82% white). At enrollment, mean ± SD disease duration was 6 ± 3 months, and Disease Activity Score in 28 joints was 5.1 ± 1.5. Over 8 years, the proportion of patients seen in annual followup declined from 100% to 91%. Over followup, 42% of patients had 0 gaps in care of >12 months, and 64% had 0 gaps >14 months. The percentage of DMARD-treated early RA patients was and remained high (95-87%), and the percentage receiving DMARDs within 14 days of diagnosis was 75%. Median time-to-DMARD therapy was 1 day, indicating DMARDs were initiated at diagnosis (90th percentile 93 days).

CONCLUSION

There was evidence of high adherence to system-level performance measures in this early RA cohort following a protocol. Small declines in performance were noted with increasing length of patient followup. Our findings are useful for performance measure benchmarking.

摘要

目的

评估全国早期类风湿关节炎(RA)队列中 3 项系统水平绩效指标的依从性。

方法

纳入于 2007-2015 年入组加拿大早期关节炎队列、符合 1987 年或 2010 年美国风湿病学会/欧洲抗风湿病联盟标准、症状持续时间<1 年且入组后随访时间≥1 年的患者。评估的绩效指标包括每年随访中 RA 患者的比例、就诊间隔超过 12 个月或超过 14 个月的次数、接受改善病情抗风湿药物(DMARD)治疗的 RA 患者比例以及从 RA 诊断到开始 DMARD 治疗的天数。结果按入组年份分层,以评估绩效的时间变化。

结果

共纳入 1763 例早期 RA 患者(平均年龄 54 岁,73%为女性,82%为白人)。入组时,平均±SD 病程为 6±3 个月,28 关节疾病活动度评分为 5.1±1.5。8 年内,每年随访中患者的比例从 100%降至 91%。随访期间,42%的患者无超过 12 个月的就诊间隔,64%的患者无超过 14 个月的就诊间隔。接受 DMARD 治疗的早期 RA 患者比例高且保持稳定(95-87%),诊断后 14 天内接受 DMARD 治疗的患者比例为 75%。中位数达到 DMARD 治疗的时间为 1 天,表明 DMARD 是在诊断时开始使用的(第 90 百分位数为 93 天)。

结论

在遵循方案的情况下,该早期 RA 队列中系统水平绩效指标的依从性很高。随着患者随访时间的延长,绩效略有下降。我们的研究结果有助于进行绩效衡量的基准测试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dc1/6001563/1d8eb9319946/ACR-70-842-g001.jpg

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