University of Calgary, Calgary, Alberta, Canada, and Arthritis Research Canada, Richmond, British Columbia, Canada.
University of Toronto, Toronto, Ontario, Canada.
Arthritis Care Res (Hoboken). 2018 Jun;70(6):842-850. doi: 10.1002/acr.23439. Epub 2018 Mar 25.
To assess adherence to 3 system-level performance measures in a national early rheumatoid arthritis (RA) cohort.
Patients enrolled in the Canadian Early Arthritis Cohort (2007-2015) who met 1987 or 2010 American College of Rheumatology/European League Against Rheumatism criteria with <1 year of symptom duration and ≥1 year of followup after enrollment were included. Performance measures assessed were the percentage of RA patients seen in yearly followup, and the number of gaps between visits of >12 or >14 months, the percentage of RA patients treated with a disease-modifying antirheumatic drug (DMARD), and days from RA diagnosis to initiation of a DMARD. Results are shown stratified by enrollment year to assess for temporal changes in performance.
A total of 1,763 early RA patients were included (mean age 54 years, 73% female, and 82% white). At enrollment, mean ± SD disease duration was 6 ± 3 months, and Disease Activity Score in 28 joints was 5.1 ± 1.5. Over 8 years, the proportion of patients seen in annual followup declined from 100% to 91%. Over followup, 42% of patients had 0 gaps in care of >12 months, and 64% had 0 gaps >14 months. The percentage of DMARD-treated early RA patients was and remained high (95-87%), and the percentage receiving DMARDs within 14 days of diagnosis was 75%. Median time-to-DMARD therapy was 1 day, indicating DMARDs were initiated at diagnosis (90th percentile 93 days).
There was evidence of high adherence to system-level performance measures in this early RA cohort following a protocol. Small declines in performance were noted with increasing length of patient followup. Our findings are useful for performance measure benchmarking.
评估全国早期类风湿关节炎(RA)队列中 3 项系统水平绩效指标的依从性。
纳入于 2007-2015 年入组加拿大早期关节炎队列、符合 1987 年或 2010 年美国风湿病学会/欧洲抗风湿病联盟标准、症状持续时间<1 年且入组后随访时间≥1 年的患者。评估的绩效指标包括每年随访中 RA 患者的比例、就诊间隔超过 12 个月或超过 14 个月的次数、接受改善病情抗风湿药物(DMARD)治疗的 RA 患者比例以及从 RA 诊断到开始 DMARD 治疗的天数。结果按入组年份分层,以评估绩效的时间变化。
共纳入 1763 例早期 RA 患者(平均年龄 54 岁,73%为女性,82%为白人)。入组时,平均±SD 病程为 6±3 个月,28 关节疾病活动度评分为 5.1±1.5。8 年内,每年随访中患者的比例从 100%降至 91%。随访期间,42%的患者无超过 12 个月的就诊间隔,64%的患者无超过 14 个月的就诊间隔。接受 DMARD 治疗的早期 RA 患者比例高且保持稳定(95-87%),诊断后 14 天内接受 DMARD 治疗的患者比例为 75%。中位数达到 DMARD 治疗的时间为 1 天,表明 DMARD 是在诊断时开始使用的(第 90 百分位数为 93 天)。
在遵循方案的情况下,该早期 RA 队列中系统水平绩效指标的依从性很高。随着患者随访时间的延长,绩效略有下降。我们的研究结果有助于进行绩效衡量的基准测试。