Becattini Cecilia, Mattei Cristian, Agnelli Giancarlo
Medicina Interna e Cardiovascolare, Università degli Studi, Perugia.
G Ital Cardiol (Rome). 2018 Jan;19(1):13-23. doi: 10.1714/2852.28775.
Clinical management of acute pulmonary embolism has changed over the years based on new evidence on diagnosis, prognostic stratification and treatment. The increasing availability of computed tomography angiography has made the diagnosis faster and accurate, although with some concern on radiation exposure and potential for overdiagnosis. The efficacy and safety of simple-to-use oral anticoagulant agents acting as selective direct inhibitors of coagulation certainly offer considerable benefits to the patients. However, the appropriate use of these agents is necessary to maintain an optimal risk-benefit ratio. This paper reports answers to ten frequently asked questions in the management of patients with suspected or proven acute pulmonary embolism.
多年来，基于诊断、预后分层和治疗方面的新证据，急性肺栓塞的临床管理发生了变化。计算机断层扫描血管造影技术的日益普及使诊断更快、更准确，尽管人们对辐射暴露和过度诊断的可能性有所担忧。作为选择性直接凝血抑制剂的简单易用口服抗凝剂的有效性和安全性无疑为患者带来了相当大的益处。然而，正确使用这些药物对于维持最佳风险效益比是必要的。本文报告了疑似或确诊急性肺栓塞患者管理中十个常见问题的答案。
