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术前心肺运动试验解读的观察者间可靠性:一项横断面研究。

Inter-observer reliability of preoperative cardiopulmonary exercise test interpretation: a cross-sectional study.

机构信息

William Harvey Research Institute, Queen Mary University of London, London, UK; Barts Health NHS Trust, London, UK.

Barts Health NHS Trust, London, UK.

出版信息

Br J Anaesth. 2018 Mar;120(3):475-483. doi: 10.1016/j.bja.2017.11.071. Epub 2017 Nov 29.

Abstract

BACKGROUND

Despite the increasing importance of cardiopulmonary exercise testing (CPET) for preoperative risk assessment, the reliability of CPET interpretation is unclear. We aimed to assess inter-observer reliability of preoperative CPET.

METHODS

We conducted a prospective, multi-centre, observational study of preoperative CPET interpretation. Participants were professionals with previous experience or training in CPET, assessed by a standardized questionnaire. Each participant interpreted 100 tests using standardized software. The CPET variables of interest were oxygen consumption at the anaerobic threshold (AT) and peak oxygen consumption (VO peak). Inter-observer reliability was measured using intra-class correlation coefficient (ICC) with a random effects model. Results are presented as ICC with 95% confidence interval, where ICC of 1 represents perfect agreement and ICC of 0 represents no agreement.

RESULTS

Participants included 8/28 (28.6%) clinical physiologists, 10 (35.7%) junior doctors, and 10 (35.7%) consultant doctors. The median previous experience was 140 (inter-quartile range 55-700) CPETs. After excluding the first 10 tests (acclimatization) for each participant and missing data, the primary analysis of AT and VO peak included 2125 and 2414 tests, respectively. Inter-observer agreement for numerical values of AT [ICC 0.83 (0.75-0.90)] and VO peak [ICC 0.88 (0.84-0.92)] was good. In a post hoc analysis, inter-observer agreement for identification of the presence of a reportable AT was excellent [ICC 0.93 (0.91-0.95)] and a reportable VO peak was moderate [0.73 (0.64-0.80)].

CONCLUSIONS

Inter-observer reliability of interpretation of numerical values of two commonly used CPET variables was good (>80%). However, inter-observer agreement regarding the presence of a reportable value was less consistent.

摘要

背景

尽管心肺运动测试(CPET)在术前风险评估中的重要性日益增加,但 CPET 解读的可靠性尚不清楚。我们旨在评估术前 CPET 的观察者间可靠性。

方法

我们进行了一项前瞻性、多中心、观察性研究,评估了术前 CPET 解读的观察者间可靠性。参与者为具有 CPET 先前经验或培训的专业人员,通过标准化问卷进行评估。每位参与者使用标准化软件对 100 次测试进行解读。感兴趣的 CPET 变量包括无氧阈(AT)时的耗氧量和峰值耗氧量(VOpeak)。观察者间可靠性使用具有随机效应模型的组内相关系数(ICC)进行测量。结果以 ICC 及其 95%置信区间表示,ICC 为 1 表示完全一致,ICC 为 0 表示无一致性。

结果

参与者包括 8/28(28.6%)临床生理学家、10(35.7%)初级医生和 10(35.7%)顾问医生。中位数的先前经验为 140(四分位距 55-700)次 CPET。排除每位参与者的前 10 次测试(适应期)和缺失数据后,对 AT 和 VOpeak 的主要分析分别包括 2125 次和 2414 次测试。AT[ICC 0.83(0.75-0.90)]和 VOpeak[ICC 0.88(0.84-0.92)]数值的观察者间一致性良好。在事后分析中,报告性 AT 存在的观察者间一致性极好[ICC 0.93(0.91-0.95)],报告性 VOpeak 存在的一致性为中度[0.73(0.64-0.80)]。

结论

两种常用 CPET 变量数值解读的观察者间可靠性良好(>80%)。然而,关于报告值存在的观察者间一致性不一致。

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