迁移的细胞需要细胞核吗？
Do migrating cells need a nucleus?
机构信息
Department of Physics and Astronomy, University of Sheffield, Sheffield, UK
出版信息
J Cell Biol. 2018 Mar 5;217(3):799-801. doi: 10.1083/jcb.201802054. Epub 2018 Feb 16.
Abstract
How the nucleus affects cell polarity and migration is unclear. In this issue, Graham et al. (2018. https://doi.org/10.1083/jcb.201706097) show that enucleated cells polarize and migrate in two but not three dimensions and propose that the nucleus is a necessary component of the molecular clutch regulating normal mechanical responses.
摘要
细胞核如何影响细胞极性和迁移尚不清楚。在本期杂志中，Graham 等人（2018 年，https://doi.org/10.1083/jcb.201706097）表明去核细胞在二维而不是三维空间中发生极化和迁移，并提出细胞核是调节正常力学反应的分子离合器的必要组成部分。
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