Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, 1955 East West Road, Honolulu, HI 96822 USA; Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong 510225, China; China Agricultural University, Beijing, 100094, China.
Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, 1955 East West Road, Honolulu, HI 96822 USA; Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong 510225, China.
Chemosphere. 2018 May;199:495-501. doi: 10.1016/j.chemosphere.2018.02.032. Epub 2018 Feb 8.
Moniliella wahieum Y12, isolated from biodiesel was used as a model organism to assess the use of lanthanum oxide (LaO) (60-80 nm) and silver oxide (AgO) (10-40 nm) nanoparticles as potential fungal inhibitors. This is the first study to investigate the use of nanoscale LaO as a eukaryotic bio-inhibitor. The AgO nanoparticles were relatively effective at inhibiting the growth of M. wahieum Y12. The half maximal effective concentration (EC) for AgO was 0.012 mg/mL as compared with 4.63 mg/mL of LaO. Fluorescein diacetate analysis showed that AgO nanoparticles significantly reduced metabolic activity in M. wahieum Y12. The results of this study indicated that AgO nanoparticles can be a nonspecific inhibitor for the treatment of M. wahieum Y12, a eukaryotic biodiesel contaminant.
从生物柴油中分离出的 Moniliella wahieum Y12 被用作模式生物，以评估氧化镧（LaO）（60-80nm）和氧化银（AgO）（10-40nm）纳米颗粒作为潜在真菌抑制剂的用途。这是首次研究将纳米级 LaO 用作真核生物生物抑制剂。AgO 纳米颗粒在抑制 M. wahieum Y12 的生长方面相对有效。与 4.63mg/mL 的 LaO 相比，AgO 的半最大有效浓度（EC）为 0.012mg/mL。荧光素二乙酸酯分析表明，AgO 纳米颗粒显著降低了 M. wahieum Y12 的代谢活性。本研究结果表明，AgO 纳米颗粒可以作为一种非特异性抑制剂，用于治疗真核生物生物柴油污染物 M. wahieum Y12。
