氧化镧纳米颗粒对从生物柴油中分离出的真菌 Moniliella wahieum Y12 的毒性。
Toxicity of lanthanum oxide nanoparticles to the fungus Moniliella wahieum Y12 isolated from biodiesel.
机构信息
Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, 1955 East West Road, Honolulu, HI 96822 USA; Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong 510225, China; China Agricultural University, Beijing, 100094, China.
Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, 1955 East West Road, Honolulu, HI 96822 USA; Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong 510225, China.
出版信息
Chemosphere. 2018 May;199:495-501. doi: 10.1016/j.chemosphere.2018.02.032. Epub 2018 Feb 8.
Moniliella wahieum Y12, isolated from biodiesel was used as a model organism to assess the use of lanthanum oxide (LaO) (60-80 nm) and silver oxide (AgO) (10-40 nm) nanoparticles as potential fungal inhibitors. This is the first study to investigate the use of nanoscale LaO as a eukaryotic bio-inhibitor. The AgO nanoparticles were relatively effective at inhibiting the growth of M. wahieum Y12. The half maximal effective concentration (EC) for AgO was 0.012 mg/mL as compared with 4.63 mg/mL of LaO. Fluorescein diacetate analysis showed that AgO nanoparticles significantly reduced metabolic activity in M. wahieum Y12. The results of this study indicated that AgO nanoparticles can be a nonspecific inhibitor for the treatment of M. wahieum Y12, a eukaryotic biodiesel contaminant.
从生物柴油中分离出的 Moniliella wahieum Y12 被用作模式生物，以评估氧化镧（LaO）（60-80nm）和氧化银（AgO）（10-40nm）纳米颗粒作为潜在真菌抑制剂的用途。这是首次研究将纳米级 LaO 用作真核生物生物抑制剂。AgO 纳米颗粒在抑制 M. wahieum Y12 的生长方面相对有效。与 4.63mg/mL 的 LaO 相比，AgO 的半最大有效浓度（EC）为 0.012mg/mL。荧光素二乙酸酯分析表明，AgO 纳米颗粒显著降低了 M. wahieum Y12 的代谢活性。本研究结果表明，AgO 纳米颗粒可以作为一种非特异性抑制剂，用于治疗真核生物生物柴油污染物 M. wahieum Y12。
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