Life Sciences Application and Research Center, Gazi University, Golbasi, 06830, Ankara, Turkey.
Environ Sci Process Impacts. 2015 Jul;17(7):1265-70. doi: 10.1039/c5em00035a.
This study demonstrates the acute toxicity of lanthanum oxide nanoparticles (La2O3 NP) on two sentinel aquatic species, fresh-water microalgae Chlorella sp. and the crustacean Daphnia magna. The morphology, size and charge of the nanoparticles were systematically studied. The algal growth inhibition assay confirmed absence of toxic effects of La2O3 NP on Chlorella sp., even at higher concentration (1000 mg L(-1)) after 72 h exposure. Similarly, no significant toxic effects were observed on D. magna at concentrations of 250 mg L(-1) or less, and considerable toxic effects were noted in higher concentrations (effective concentration [EC50] 500 mg L(-1); lethal dose [LD50] 1000 mg L(-1)). In addition, attachment of La2O3 NP on aquatic species was demonstrated using microscopy analysis. This study proved to be beneficial in understanding acute toxicity in order to provide environmental protection as part of risk assessment strategies.
本研究证明了氧化镧纳米粒子（La2O3 NP）对两种水生态指示物种——淡水微藻小球藻和甲壳类动物大型溞的急性毒性。系统研究了纳米粒子的形态、尺寸和荷电性。藻类生长抑制试验证实，La2O3 NP 对小球藻没有毒性作用，即使在 72 小时暴露于较高浓度（1000 mg L(-1))时也没有。同样，在浓度为 250 mg L(-1)或更低时，对大型溞没有观察到明显的毒性作用，而在更高浓度时则观察到相当大的毒性作用（有效浓度 [EC50] 500 mg L(-1)；半数致死浓度 [LD50] 1000 mg L(-1)）。此外，还使用显微镜分析证明了 La2O3 NP 在水生生物上的附着。这项研究有助于了解急性毒性，以便作为风险评估策略的一部分提供环境保护。
