Odom H, Davis J L, Dinh H, Baker B J, Roberts W C, Murphy M L
Am J Cardiol. 1986 Oct 1;58(9):801-4. doi: 10.1016/0002-9149(86)90357-7.
Use of total 12-lead QRS electrocardiographic voltage as a criterion for left ventricular (LV) hypertrophy has been of recent interest. Although upper and lower limits of QRS voltage for individual electrocardiographic leads have been reported in clinically healthy men and women, the upper limit of total 12-lead QRS voltage has not been established in adults free of cardiopulmonary disease by clinical and necropsy criteria. Therefore, the total QRS voltage from all 12 electrocardiographic leads was determined in 30 autopsied men known to be free of cardiopulmonary disease by clinical assessment and by a special cardiac examination using postmortem coronary angiography and chamber partition determination of LV weight. Gross heart weight, LV weight and total QRS voltage are reported. Comparisons were made between disease-free patients and previously reported patients with aortic valve stenosis, aortic regurgitation and cardiac amyloidosis with respect to total QRS voltage and gross heart weight. Total QRS voltage and gross heart weight were significantly greater in patients with severe aortic stenosis (mean 245 mm) and severe aortic regurgitation (mean 274 mm) than in our patients (mean 127 mm). Total QRS voltage was significantly less, whereas gross heart weight was significantly greater in patients with cardiac amyloidosis (mean 101 mm) than in our normal subjects (mean 127 mm). These data provide a basis for evaluating the total 12-lead QRS voltage as a criterion for LV hypertrophy.
将12导联心电图QRS波总电压用作左心室（LV）肥厚的标准近来受到关注。尽管已报道了临床健康男性和女性个体心电图导联QRS波电压的上限和下限，但尚未根据临床和尸检标准在无心肺疾病的成年人中确定12导联心电图QRS波总电压的上限。因此，通过临床评估以及使用死后冠状动脉造影和左心室重量的腔室划分测定的特殊心脏检查，对30名已知无心肺疾病的男性尸检对象的12导联心电图QRS波总电压进行了测定。报告了心脏总重量、左心室重量和QRS波总电压。就QRS波总电压和心脏总重量而言，对无疾病患者与先前报道的主动脉瓣狭窄、主动脉瓣关闭不全和心脏淀粉样变性患者进行了比较。重度主动脉瓣狭窄患者（平均245毫米）和重度主动脉瓣关闭不全患者（平均274毫米）的QRS波总电压和心脏总重量显著高于我们的患者（平均127毫米）。心脏淀粉样变性患者（平均101毫米）的QRS波总电压显著低于我们的正常受试者（平均127毫米），而心脏总重量显著高于正常受试者。这些数据为评估12导联心电图QRS波总电压作为左心室肥厚的标准提供了依据。
