He Hong, Chen Xiaolian, Liu Hongshan, Wu Jiaochan, Zhong Xingwu
Hainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 19 Xiuhua Road, Haikou, China.
Zhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, China.
BMC Ophthalmol. 2018 Feb 17;18(1):47. doi: 10.1186/s12886-018-0702-9.
Postoperative endophthalmitis after cataract surgery is a severe eye infection that can lead to irreversible blindness in the affected eye. The characteristics, treatment and prognosis of this disease vary because of its association with different pathogens. Here, we report what is possibly the first case of endophthalmitis after cataract surgery to be associated with the rare pathogen Earliella scabrosa.
A 56-year-old man from Hainan Island (China) with a history of phacoemulsification and type II diabetes mellitus underwent intraocular lens (IOL) implantation. He later presented with progressive endophthalmitis in his right eye. IOL explantation with capsular bag removal and a 23G pars plana vitrectomy combined with a silicone oil tamponade was performed. The infection was cleared without recurrence, and the patient's visual acuity improved from light perception to 20/200 in the right eye. An in vitro culture determined that the causative pathogen was Earliella scabrosa, and this result was confirmed by an internal transcribed spacer (ITS) sequence analysis.
Earliella scabrosa has never been reported as an infectious agent in human eyes, and its clinical significance remains unknown. Here, we report a rare case of Earliella scabrosa-associated endophthalmitis after cataract surgery. The fungal infection presented as an acute attack and was successfully treated with vitrectomy.
白内障手术后的眼内炎是一种严重的眼部感染，可导致患眼不可逆性失明。由于其与不同病原体相关，该疾病的特征、治疗及预后各不相同。在此，我们报告了可能是首例白内障手术后与罕见病原体粗糙早盘菌相关的眼内炎病例。
一名来自中国海南岛的56岁男性，有超声乳化白内障吸除术病史及II型糖尿病，接受了人工晶状体植入术。他随后右眼出现进行性眼内炎。进行了人工晶状体取出联合囊袋摘除术以及23G经睫状体平坦部玻璃体切除术并联合硅油填充。感染得以清除且未复发，患者右眼视力从光感提高到了20/200。体外培养确定致病病原体为粗糙早盘菌，该结果经内转录间隔区（ITS）序列分析得以证实。
粗糙早盘菌从未被报道为人类眼部的感染病原体，其临床意义尚不清楚。在此，我们报告了一例罕见的白内障手术后与粗糙早盘菌相关的眼内炎病例。该真菌感染表现为急性发作，通过玻璃体切除术成功治愈。
