Ota Shinichiro, Fujikura Yuji, Yamamoto Takayuki, Maki Yohei, Kurokawa Atsushi, Maeda Takuya, Kanoh Soichiro, Kawana Akihiko
Division of Infectious Diseases and Respiratory Medicine, Department of Internal Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Division of Infectious Diseases and Respiratory Medicine, Department of Internal Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
J Infect Chemother. 2018 Jun;24(6):487-491. doi: 10.1016/j.jiac.2018.01.011. Epub 2018 Feb 15.
Primary effusion lymphoma (PEL) is a rare subtype of large B-cell lymphoma associated with human herpesvirus-8. Most cases are co-infected with Epstein-Barr virus (EBV). The prognosis of PEL is extremely poor and no optimal treatment regimen has been established. We report a case of EBV-negative PEL in a 49-year-old human immunodeficiency virus-positive man, presenting with massive bilateral pleural effusion.