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双动全髋关节置换术与双极人工股骨头置换术治疗股骨颈骨折的比较:199 髋回顾性病例对照研究。

Comparison of dual mobility total hip arthroplasty and bipolar arthroplasty for femoral neck fractures: A retrospective case-control study of 199 hips.

机构信息

Service de chirurgie orthopédique et traumatologique, CH intercommunal le Raincy-Montfermeil, 10, rue du Général-Leclerc, 93370 Montfermeil, France.

Service de chirurgie orthopédique et traumatologique, CH intercommunal le Raincy-Montfermeil, 10, rue du Général-Leclerc, 93370 Montfermeil, France.

出版信息

Orthop Traumatol Surg Res. 2018 May;104(3):369-375. doi: 10.1016/j.otsr.2018.01.006. Epub 2018 Feb 15.

Abstract

BACKGROUND

The choice between performing total hip arthroplasty (THA) or hemiarthroplasty (HA) is not straightforward in older patients with femoral neck fracture, particularly when co-morbidities are factored in. This led us to carry out a case-control study to determine (1) the rate of mechanical complications for these two types of implants, and (2) the rate of medical complications and mortality.

HYPOTHESIS

THA with dual mobility cup (DM) will result in fewer mechanical complications than HA.

PATIENTS AND METHODS

This was a single-center, retrospective case-control study. Between 2010 and 2015, all patients with a femoral neck fracture treated by HA or DM THA were included. The primary outcome was the occurrence of any type of surgical complication. The Charlson Co-morbidity Index (CCI) and the independence during Activities of Daily Living (ADL) score were calculated for every patient. Two subgroups of patients were made based on whether they met frailty criteria. The effect of covariates on 1-year mortality was controlled using Cox's proportional hazards regression model.

RESULTS

The cohort consisted of 101 HA and 98 THA procedures in 193 patients (139 women, 54 men) with a mean age of 80.6years (range, 76-101). The mean follow-up was 24.2months (range, 0-83) with a median of 14.5months. Fifteen of the HA hips (15%) had surgical complication, of which 10 were posterior dislocations (10%). Ten patients in the HA cohort had a serious medical complication (10%). Ten of the THA hips (10%) had a mechanical complication, including three posterior dislocations (3%) and four infections (4%). Nine patients in the THA cohort had a medical complication (9%). There were significantly fewer posterior dislocations in the THA hips (p = 0.05). In the subgroup analysis, the 117 patients (58%) who met the frailty criteria had a significantly lower dislocation rate after undergoing THA (p = 0.048). After adjusting on age, ADL and CCI score, the dislocation rate no longer differed significantly between the two groups (p = 0.1). The dislocation rate was lower in the THA hips only in the "frail" patients (Odds ratio = 0.137, 95% CI: [0.003-0.97] (p = 0.04)). There was no difference in the dislocation rate in the "non-frail" patients. The overall 1-year mortality was 85% [95% CI: 78-94%]. It was 78% [95% CI: 69-86%] for the HA hips and 88% [95% CI: 82-95%] for the THA hips (p = 0.01). After factoring in the impact of age, CCI and ADL, the differences in the 1-year mortality between HA and THA were no longer present (p = 0.42). Thus, there is no increased risk of mortality in THA patients.

DISCUSSION

When the CCI and independence level are taken into consideration, the frailest patients can undergo DM THA to reduce the dislocation risk, without increasing the mortality rate at 1year. Patients who are not frail will benefit equally from undergoing HA or THA.

LEVEL OF EVIDENCE

III, case-control study.

摘要

背景

在考虑到合并症的情况下,老年股骨颈骨折患者在选择全髋关节置换术(THA)还是半髋关节置换术(HA)并不简单。这导致我们进行了一项病例对照研究,以确定(1)这两种类型植入物的机械并发症发生率,以及(2)医疗并发症和死亡率。

假设

双动杯(DM)THA 的机械并发症发生率低于 HA。

患者和方法

这是一项单中心、回顾性病例对照研究。2010 年至 2015 年期间,我们纳入了所有接受 HA 或 DM THA 治疗的股骨颈骨折患者。主要结局是任何类型的手术并发症的发生情况。为每位患者计算 Charlson 合并症指数(CCI)和日常生活活动(ADL)评分的独立性。根据是否符合虚弱标准,将患者分为两个亚组。使用 Cox 比例风险回归模型控制协变量对 1 年死亡率的影响。

结果

该队列包括 193 名患者(139 名女性,54 名男性)的 101 例 HA 和 98 例 THA 手术,平均年龄为 80.6 岁(范围,76-101)。平均随访时间为 24.2 个月(范围,0-83),中位数为 14.5 个月。15 例 HA 髋关节(15%)出现手术并发症,其中 10 例为后脱位(10%)。HA 组中有 10 例患者出现严重的医疗并发症(10%)。10 例 THA 髋关节(10%)出现机械并发症,包括 3 例后脱位(3%)和 4 例感染(4%)。THA 组中有 9 例患者出现医疗并发症(9%)。THA 髋关节的后脱位明显较少(p=0.05)。在亚组分析中,符合虚弱标准的 117 名患者(58%)在接受 THA 后脱位率显著降低(p=0.048)。调整年龄、ADL 和 CCI 评分后,两组之间的脱位率不再有显著差异(p=0.1)。THA 髋关节的脱位率仅在“虚弱”患者中较低(优势比=0.137,95%CI:[0.003-0.97](p=0.04))。在“非虚弱”患者中,脱位率没有差异。总体 1 年死亡率为 85%[95%CI:78-94%]。HA 髋关节为 78%[95%CI:69-86%],THA 髋关节为 88%[95%CI:82-95%](p=0.01)。考虑到 CCI 和 ADL 的影响后,HA 和 THA 之间的 1 年死亡率差异不再存在(p=0.42)。因此,THA 患者的死亡率没有增加的风险。

讨论

当考虑 CCI 和独立水平时,最虚弱的患者可以接受 DM THA 以降低脱位风险,而不会增加 1 年的死亡率。不虚弱的患者将同样受益于 HA 或 THA。

证据水平

III 级,病例对照研究。

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