Sabour Sahar, Arzanlou Mohsen, Vaez Hamid, Rahimi Giti, Sahebkar Amirhossein, Khademi Farzad
Department of Microbiology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
Department of Microbiology, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran.
Arch Gynecol Obstet. 2018 May;297(5):1101-1113. doi: 10.1007/s00404-018-4722-8. Epub 2018 Feb 17.
Bacterial vaginosis (BV) is a vaginal disorder which occurs either symptomatic or asymptomatic because of an imbalance between HO-producing Lactobacillus and Gardnerella vaginalis in the vagina. This systematic review and meta-analysis is the first to determine the prevalence of BV in pregnant and non-pregnant women in Iran.
We used national (SID, Irandoc, Iranmedex and Magiran) and international (PubMed, Scopus, Google Scholar and ISI web of knowledge) electronic databases to systematically search and collect available studies using related keywords (up to 1 December 2017). Inclusion and exclusion criteria were defined to select eligible studies.
The overall prevalence of BV among Iranian women was 18.9% (95% CI 14-25). Gardnerella vaginalis was the most prevalent isolated bacteria. The prevalence of BV in non-pregnant women was 28% (95% CI 15.1-45.9) which was higher compared with pregnant women who had a prevalence of 16.5% (95% CI 12.5-21.6).
The present review revealed a high prevalence of BV in non-pregnant women. Given that BV is associated with a series of reproductive complications such as infertility, taking preventive measures such as awareness of patients as well as monitoring and controlling of syndrome are essential.
细菌性阴道病（BV）是一种阴道疾病，由于阴道中产生过氧化氢的乳酸杆菌与阴道加德纳菌之间的失衡，可表现为有症状或无症状。本系统评价和荟萃分析首次确定了伊朗孕妇和非孕妇中BV的患病率。
我们使用国内（SID、伊朗文献数据库、伊朗医学数据库和伊朗科学数据库）和国际（PubMed、Scopus、谷歌学术和科学网）电子数据库，使用相关关键词进行系统检索并收集可用研究（截至2017年12月1日）。定义纳入和排除标准以选择符合条件的研究。
伊朗女性中BV的总体患病率为18.9%（95%置信区间14 - 25）。阴道加德纳菌是最常见的分离细菌。非孕妇中BV的患病率为28%（95%置信区间15.1 - 45.9），高于患病率为16.5%（95%置信区间12.5 - 21.6）的孕妇。
本综述显示非孕妇中BV的患病率较高。鉴于BV与一系列生殖并发症如不孕症有关，采取预防措施如提高患者意识以及监测和控制该综合征至关重要。
