Women's College Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada.
Department of Electrical and Computer Engineering, Ryerson University, Toronto, Ontario, Canada.
J Psychosom Res. 2018 Mar;106:70-72. doi: 10.1016/j.jpsychores.2018.01.009. Epub 2018 Jan 17.
About 8% of U.S women are prescribed antidepressant medications around the time of pregnancy. Decisions about medication use in pregnancy can be swayed by the opinion of family, friends and online media, sometimes beyond the advice offered by healthcare providers. Exploration of the online social network response to research on antidepressant use in pregnancy could provide insight about how to optimize decision-making in this complex area.
For all 17 research articles published on the safety of antidepressant use in pregnancy in 2012, we sought to explore online social network activity regarding antidepressant use in pregnancy, via Twitter, in the 48h after a study was published, compared to the social network activity in the same period 1week prior to each article's publication.
Online social network activity about antidepressants in pregnancy quickly doubled upon study publication. The increased activity was driven by studies demonstrating harm associated with antidepressants, lower-quality studies, and studies where abstracts presented relative versus absolute risks.
These findings support a call for leadership from medical journals to consider how to best incentivize and support a balanced and clear translation of knowledge around antidepressant safety in pregnancy to their readership and the public.
大约 8%的美国女性在怀孕前后会被开抗抑郁药物。关于孕期用药的决定可能会受到家人、朋友和网络媒体的影响,有时甚至超出了医疗保健提供者的建议。探索针对孕期使用抗抑郁药物的研究在网络社交网络上的反应,可以深入了解如何优化这一复杂领域的决策。
对于 2012 年发表的所有 17 篇关于抗抑郁药在孕期使用安全性的研究文章,我们试图通过 Twitter 探索在研究发表后 48 小时内与孕期抗抑郁药使用相关的网络社交网络活动,与每篇文章发表前一周同一时期的网络社交网络活动进行比较。
研究发表后,关于孕期使用抗抑郁药物的网络社交网络活动迅速增加了一倍。增加的活动是由与抗抑郁药相关的危害、低质量的研究以及研究中呈现相对风险与绝对风险的研究驱动的。
这些发现支持医学期刊的领导层呼吁,考虑如何最好地激励和支持将关于孕期抗抑郁药安全性的知识以平衡和清晰的方式转化为读者和公众。