Pannuti F, Strocchi E, Longhi A, Comparsi R, Camaggi C M
Chemioterapia. 1986 Aug;5(4):237-9.
A comparison has been made between the absorption of oral medroxyprogesterone acetate (MPA) in an aqueous suspension preparation and in syrup form. Plasma drug profiles were measured after a single administration of the two formulations in 17 advanced cancer patients. On average the standard form (aqueous suspension) gave peak levels which were lower than the syrup mixture. However, the wide intersubject spread in MPA plasma levels observed in both groups did not allow any statistical significance to be assigned to this difference.
已对醋酸甲羟孕酮（MPA）水悬浮制剂和糖浆剂的口服吸收情况进行了比较。在17例晚期癌症患者中单次给予这两种制剂后测量了血浆药物浓度曲线。平均而言，标准剂型（水悬浮剂）的峰值水平低于糖浆混合物。然而，两组中观察到的MPA血浆水平在个体间差异较大，因此无法将这种差异赋予任何统计学意义。
