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一例下颌下区神经鞘瘤

A Case of Schwannoma of the Submandibular Region.

作者信息

Bamgbose Babatunde O, Sato Akiko, Yanagi Yoshinobu, Hisatomi Miki, Takeshita Yohei, Sugianto Irfan, Asaumi Junichi

机构信息

Department of Oral and Maxillofacial Radiology, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Department of Dentomaxillofacial Radiology and Oral Diagnosis, Okayama University Hospital, Okayama, Japan.

出版信息

Open Dent J. 2018 Jan 29;12:12-18. doi: 10.2174/1874210601812010012. eCollection 2018.

Abstract

BACKGROUND

We herein described a rare case of schwannoma of the hypoglossal nerve in the submandibular region with diagnostic imaging and histopathological findings.

CASE REPORT

A 31-years-old woman has had a palpable firm, rubbery, freely mobile mass in the submandibular region. Of imaging, MR images showed homogeneous isointensity on T1-weighted imaging (T1-WI), heterogeneous hypointensity on T2-WI, heterogeneous hyperintensity on short T1 inversion recovery (STIR), and heterogeneous enhancement on contrast-enhanced T1-WI. A clear capsule was observed on the margin and showed hypointense on T2-WI. Dynamic MRI showed heterogeneous gradual increased enhancement. The uptake of contrast medium was regionally slow. Diagnostic imaging using CT and MRI was suspected of salivary gland tumor or neurogenic tumor. In consideration of imaging diagnosis, a pleomorphic adenoma or a schwannoma was suspected. Final diagnosis was confirmed on the basis of histopathological finding and intraoperative findings.

CONCLUSION

  1. Histopathologic examination is inevitable, because MR findings are not specific.2. Schwannomas were said to have specific MRI properties, including specific signs (split-fat sign, fascicular sign, target sign). However, they are not always observed.3. This case confirmed the differential diagnosis on the basis of the intraoperative finding that the tumor was continuous with the hypoglossal nerve.
摘要

背景

我们在此描述了一例罕见的下颌下区舌下神经鞘瘤的诊断性影像学和组织病理学表现。

病例报告

一名31岁女性下颌下区可触及一个质地坚硬、似橡胶、活动自如的肿块。影像学检查中,磁共振成像(MR)在T1加权成像(T1-WI)上显示均匀等信号,在T2加权成像(T2-WI)上显示不均匀低信号,在短T1反转恢复序列(STIR)上显示不均匀高信号,在增强T1-WI上显示不均匀强化。边缘可见清晰的包膜,在T2-WI上呈低信号。动态MRI显示不均匀渐进性强化增加。造影剂摄取局部缓慢。CT和MRI诊断性成像怀疑为涎腺肿瘤或神经源性肿瘤。综合影像学诊断,怀疑为多形性腺瘤或神经鞘瘤。最终诊断根据组织病理学检查结果和术中所见得以证实。

结论

  1. 由于MR表现不具特异性,组织病理学检查必不可少。2. 据说神经鞘瘤具有特定的MRI特征,包括特定征象(脂肪分离征、束状征、靶征)。然而,并非总能观察到这些征象。3. 该病例基于术中发现肿瘤与舌下神经相连,从而证实了鉴别诊断。
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ba/5806283/70624a72a38c/TODENTJ-12-12_F1.jpg

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