Doneva Miglena, Pashkouleva Dessislava
Faculty of Pharmacy, Medical University-Sofia, 2 Dunav Str., 1000 Sofia, Bulgaria.
Institute of Mechanics, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 4, 1113 Sofia, Bulgaria.
Biomed Mater Eng. 2018;29(2):147-158. doi: 10.3233/BME-171719.
Understanding the biomechanical properties of hernia meshes is essential in facilitating their selection. The aim of this study was to evaluate the mechanical compatibility of hernia meshes and human abdominal fascia and assess their applicability in hernia repair.
Uniaxial tensile tests were performed. A total of eight hernia meshes were tested - three standard meshes (Surgimesh®, Surgipro™, TecnoMesh®) and five light-weight meshes (Optilene®, TiO2Mesh™, Parietex™, Vypro™ II, Ultrapro™).
The secant modulus at 5% strain and the level of orthotropy (the ratio between tensile stress in the longitudinal and the transversal direction) at 5% strain were calculated from the stress-stretch ratio curves. The impact of pore size and thickness on the elastic properties of these meshes was determined. The relationships between density and elasticity as well as between elasticity and the strain developed at 16 N/cm load were presented. The resulting mechanical properties of meshes were compared to the elasticity, orthotropy and deformability of human abdominal fascia.
Vypro™ II and Parietex™ brands display properties similar to those of fascia in both directions. The TiO2Mesh™ and Ultrapro™ display deformability close to the deformability at 16 N/cm of the fascia transversalis. Only the Vypro™ II brand's orthotropy is similar to that of fascia.
了解疝修补补片的生物力学特性对于促进其选择至关重要。本研究的目的是评估疝修补补片与人体腹部筋膜的力学相容性,并评估它们在疝修补中的适用性。
进行单轴拉伸试验。共测试了八种疝修补补片——三种标准补片(Surgimesh®、Surgipro™、TecnoMesh®)和五种轻质补片(Optilene®、TiO2Mesh™、Parietex™、Vypro™ II、Ultrapro™)。
根据应力-应变比曲线计算5%应变时的割线模量和5%应变时的正交各向异性水平(纵向和横向拉伸应力之比)。确定了孔径和厚度对这些补片弹性性能的影响。给出了密度与弹性以及弹性与16 N/cm载荷下产生的应变之间的关系。将所得补片的力学性能与人体腹部筋膜的弹性、正交各向异性和可变形性进行比较。
Vypro™ II和Parietex™品牌在两个方向上均表现出与筋膜相似的特性。TiO2Mesh™和Ultrapro™的可变形性接近腹横筋膜在16 N/cm时的可变形性。只有Vypro™ II品牌的正交各向异性与筋膜相似。