高凝状态与血管疾病
Hypercoagulability and Vascular Disease.
作者信息
Taher Ali T, Cappellini Maria Domenica, Bou-Fakhredin Rayan, Coriu Daniel, Musallam Khaled M
机构信息
Department of Internal Medicine, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, PO Box 11-0236, Beirut 11072020, Lebanon.
Department of Medicine, Ca' Granda Foundation IRCCS, Milan 20122, Italy; Department of Clinical Science and Community, University of Milan, Milan 20122, Italy.
出版信息
Hematol Oncol Clin North Am. 2018 Apr;32(2):237-245. doi: 10.1016/j.hoc.2017.11.001. Epub 2017 Dec 1.
The presence of a high incidence of thrombotic events, mainly in nontransfusion-dependent β-thalassemia syndromes, has led to the identification of a hypercoagulable state in thalassemia patients. This article highlights the mechanisms leading to hypercoagulability in thalassemia. It also discusses the clinical experience and available evidence on prevention and management approaches.
血栓形成事件的高发生率主要存在于非输血依赖型β地中海贫血综合征中，这已促使人们识别出地中海贫血患者的高凝状态。本文重点介绍了导致地中海贫血患者高凝状态的机制。它还讨论了关于预防和管理方法的临床经验及现有证据。
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