Department of Microbiology, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Section of Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Microbiol Res. 2018 Mar;207:161-169. doi: 10.1016/j.micres.2017.11.016. Epub 2017 Dec 1.
For a long a time programmed cell death was thought to be a unique characteristic of higher eukaryotes, but evidence has accumulated showing that programmed cell death is a universal phenomenon in all life forms. Many different types of bacterial programmed cell death systems have been identified, rivalling the eukaryotic systems in diversity. Bacteria are singular, seemingly independently living organisms, however they are part of complex communities. Being part of a community seems indispensable for survival in different environments. This review is focussed on the mechanism of and reasons for bacterial programmed cell death in the context of bacterial communities.
长期以来,程序性细胞死亡被认为是高等真核生物所特有的一种现象,但越来越多的证据表明,程序性细胞死亡是所有生命形式中普遍存在的一种现象。已经鉴定出许多不同类型的细菌程序性细胞死亡系统,其多样性可与真核系统相媲美。细菌是一种单独的、看似独立的生物体,但它们是复杂群落的一部分。作为群落的一部分,对于在不同环境中生存似乎是必不可少的。本综述重点讨论了细菌群落中细菌程序性细胞死亡的机制和原因。