Kilani Rami, Aleyadeh Wesam, Atieleh Luay Abu, Al Suleimat Abdul Mane, Khadra Maysa, Hawamdeh Hassan M
Hashemite University, Zarqa, Jordan.
Hashemite University, Zarqa, Jordan.
Taiwan J Obstet Gynecol. 2018 Feb;57(1):32-39. doi: 10.1016/j.tjog.2017.12.006.
To evaluate inter-observer variability and reproducibility of ultrasound measurements for fetal biometric parameters.
A prospective cohort study was implemented in two tertiary care hospitals in Amman, Jordan; Prince Hamza Hospital and Albashir Hospital. 192 women with a singleton pregnancy at a gestational age of 18-36 weeks were the participants in the study. Transabdominal scans for fetal biometric parameter measurement were performed on study participants from the period of November 2014 to March 2015. Women who agreed to participate in the study were administered two ultrasound scans for head circumference, abdominal circumference and femur length. The correlation coefficient was calculated. Bland-Altman plots were used to analyze the degree of measurement agreement between observers. Limits of agreement ± 2 SD for the differences in fetal biometry measurements in proportions of the mean of the measurements were derived. Main outcome measures examine the reproducibility of fetal biometric measurements by different observers.
High inter-observer inter-class correlation coefficient (ICC) was found for femur length (0.990) and abdominal circumference (0.996) where Bland-Altman plots showed high degrees of agreement. The highest degrees of agreement were noted in the measurement of abdominal circumference followed by head circumference. The lowest degree of agreement was found for femur length measurement. We used a paired-sample t-test and found that the mean difference between duplicate measurements was not significant (P > 0.05).
Biometric fetal parameter measurements may be reproducible by different operators in the clinical setting with similar results. Fetal head circumference, abdominal circumference and femur length were highly reproducible. Large organized studies are needed to ensure accurate fetal measurements due to the important clinical implications of inaccurate measurements.
评估超声测量胎儿生物测量参数时观察者间的变异性和可重复性。
在约旦安曼的两家三级护理医院——哈姆扎王子医院和阿尔巴希尔医院开展了一项前瞻性队列研究。192名单胎妊娠、孕周为18 - 36周的女性参与了该研究。2014年11月至2015年3月期间,对研究参与者进行经腹扫描以测量胎儿生物测量参数。同意参与研究的女性接受了两次超声扫描,测量头围、腹围和股骨长度。计算相关系数。采用布兰德 - 奥特曼图分析观察者之间的测量一致性程度。得出胎儿生物测量差异的一致性界限±2标准差占测量均值的比例。主要观察指标为不同观察者对胎儿生物测量的可重复性。
股骨长度(0.990)和腹围(0.996)的观察者间组内相关系数(ICC)较高,布兰德 - 奥特曼图显示一致性程度较高。腹围测量的一致性程度最高,其次是头围。股骨长度测量的一致性程度最低。我们采用配对样本t检验,发现重复测量之间的平均差异不显著(P>0.05)。
在临床环境中,不同操作者对胎儿生物测量参数的测量可能具有可重复性,结果相似。胎儿头围、腹围和股骨长度具有高度可重复性。由于测量不准确具有重要的临床意义,因此需要开展大型有组织的研究以确保准确的胎儿测量。