Markowska Joanna, Szopa Monika, Zawadzki Marcin, Piekoszewski Wojciech
Arch Med Sadowej Kryminol. 2017;67(3):201-213. doi: 10.5114/amsik.2017.73192.
Biological materials used in toxicological analyses in forensic medicine traditionally include blood, urine and vitreous humour. Forensic use of the vitreous body is mostly due to the need to assess the endogenous concentration of ethyl alcohol in the process of human body decomposition. The vitreous body is an underestimated biological material, even though its biochemical properties and anatomical location make it suitable for specific forensic toxicology tests as a reliable material for the preparation of forensic expert opinions. Based on the available literature the paper gathers information on the biochemical structure of the vitreous body, ways to secure the material after collection and its use in postmortem diagnostics. Specific applications of the vitreous humour for biochemical and toxicological tests are discussed, with a focus on its advantages and limitations in forensic medical assessment which are attributable to its biochemical properties, anatomical location and limited scientific studies on the distribution of xenobiotics in the vitreous body.
法医学中毒理学分析中使用的生物材料传统上包括血液、尿液和玻璃体液。玻璃体液在法医学中的应用主要是由于在人体分解过程中需要评估乙醇的内源性浓度。玻璃体液是一种被低估的生物材料，尽管其生化特性和解剖位置使其适合作为制备法医专家意见的可靠材料用于特定的法医毒理学检测。基于现有文献，本文收集了有关玻璃体液生化结构、采集后材料的保存方法及其在死后诊断中的应用的信息。讨论了玻璃体液在生化和毒理学检测中的具体应用，重点关注其在法医评估中的优点和局限性，这些优点和局限性归因于其生化特性、解剖位置以及关于异生物素在玻璃体液中分布的有限科学研究。
