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女性不孕症的外科矫正:101例手术结果与失败原因分析

Surgical correction of female infertility. An analysis of results and failures in 101 cases.

作者信息

Fredricsson B, Rosenborg L

出版信息

Acta Obstet Gynecol Scand. 1986;65(5):421-5. doi: 10.3109/00016348609157376.

DOI:10.3109/00016348609157376
PMID:2946137
Abstract

During the 1970s, surgery undertaken to remedy infertility at Sabbatsberg Hospital in Stockholm involved macrosurgical techniques. The patients described here had the same pathology on either side. Sixty-three underwent different procedures for the correction of tubal pathology at laparotomy, while 20 patients had lysis of adhesions performed at laparoscopy. A further 18 patients were operated on for ovarian endometriosis. The results in terms of conceptions (ranging from 43 to 60%, depending upon the type of operation) were similar to those reported from microsurgery, but the incidence of ectopic pregnancy was higher. Second-look laparoscopy revealed the presence of adhesions and tubal block in a significant number of patients, though less often in those who ultimatively conceived. There was no difference in semen findings between patients who conceived and those who did not. Postoperative adhesions are responsible for many surgical failures, but refined methods of surgery may reduce the risk of future ectopic gestation. Only a limited number of cases remain where persistence of infertility may be due to minor anatomical or functional defects not amenable to present-day clinical evaluation.

摘要

20世纪70年代,斯德哥尔摩萨巴茨贝里医院为治疗不孕症所进行的手术采用的是宏观手术技术。这里描述的患者双侧病理情况相同。63例患者在剖腹手术中接受了不同的输卵管病理矫正手术,20例患者在腹腔镜检查时进行了粘连松解术。另有18例患者因卵巢子宫内膜异位症接受了手术。受孕结果(根据手术类型不同,受孕率在43%至60%之间)与显微手术报告的结果相似,但异位妊娠的发生率更高。二次腹腔镜检查显示,相当多的患者存在粘连和输卵管堵塞,不过最终受孕的患者中这种情况较少见。受孕患者和未受孕患者的精液检查结果没有差异。术后粘连是许多手术失败的原因,但精细的手术方法可能会降低未来发生异位妊娠的风险。只有少数病例的不孕症持续存在可能是由于目前临床评估无法检测到的微小解剖或功能缺陷。

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