Abuelo D, Barsel-Bowers G, Busch W, Pueschel S, Pezzullo J
Am J Med Genet. 1986 Oct;25(2):365-7. doi: 10.1002/ajmg.1320250223.
This study was performed to determine if sibs and other relatives of individuals with trisomy 21 are themselves at increased risk for having offspring with trisomy 21. The results suggest that the reproductive risk to these relatives is not increased beyond the risk to the general population.
本研究旨在确定21三体综合征患者的同胞及其他亲属生育21三体综合征患儿的风险是否增加。结果表明,这些亲属的生育风险并未高于普通人群。